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Volume 22, Number 9—September 2016
Dispatch

Mutation in West Nile Virus Structural Protein prM during Human Infection

Yaniv LustigComments to Author , Robert Lanciotti, Musa Hindiyeh, Nathan Keller, Ron Milo, Shlomo Mayan, and Ella Mendelson
Author affiliations: Sheba Medical Center, Tel-Hashomer, Israel (Y. Lustig, M. Hindiyeh, N. Keller, E. Mendelson); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (R.S. Lanciotti); School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel (M. Hindiyeh, E. Mendelson); Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er sheva, Israel (R. Milo); Barzilai Medical Center, Ashkelon, Israel (R. Milo, S. Mayan)

Main Article

Figure

Phylogenetic analysis of West Nile virus (WNV) lineage 1 isolate from a patient with persistent WNV infection, Israel, 2014, compared with reference strains. The analysis was conducted on 96% of the WNV nucleotide sequence using the neighbor-joining method implemented in MEGA 6.0 software (http://www.megasoftware.net). The robustness of branching pattern was tested by 1,000 bootstrap replications. The percentage of successful bootstrap replicates is indicated at nodes, showing only values of &gt

Figure. Phylogenetic analysis of West Nile virus (WNV) lineage 1 isolate from a patient with persistent WNV infection, Israel, 2014, compared with reference strains. The analysis was conducted on 96% of the WNV nucleotide sequence using the neighbor-joining method implemented in MEGA 6.0 software (http://www.megasoftware.net). The robustness of branching pattern was tested by 1,000 bootstrap replications. The percentage of successful bootstrap replicates is indicated at nodes, showing only values of >70%. A WNV lineage 2 sequence obtained from strain ITA 13 (GenBank no. KF647252) was used as an outgroup. Bold indicates the WNV lineage 1 strain sequenced in this study Scale bar indicates nucleotide substitutions per site.

Main Article

Page created: August 16, 2016
Page updated: August 16, 2016
Page reviewed: August 16, 2016
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