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Volume 23, Number 1—January 2017

Prolonged Detection of Zika Virus in Vaginal Secretions and Whole Blood

Kristy O. MurrayComments to Author , Rodion Gorchakov, Anna R. Carlson, Rebecca Berry, Lilin Lai, Muktha Natrajan, Melissa N. Garcia, Armando Correa, Shital M. Patel, Kjersti Aagaard, and Mark J. Mulligan
Author affiliations: Baylor College of Medicine, Houston, Texas, USA (K.O. Murray, R. Gorchakov, R. Berry, M.N. Garcia, A. Correa, S.M. Patel, K. Aagaard); Texas Children’s Hospital, Houston (K.O. Murray, R. Gorchakov, R. Berry, M.N. Garcia, A. Correa, S.M. Patel, K. Aagaard); Baylor St. Luke’s General Hospital, Houston (A.R. Carlson); Emory University School of Medicine, Atlanta, GA, USA (L. Lai, M. Natrajan, M.J. Mulligan)

Main Article


Timeline of acute signs and symptoms and clinical progression/resolution for a 26-year-old woman infected with Zika virus who returned from Honduras to the United States

Day after illness onset Signs and symptoms and clinical progression
Red, mottled, flat rash on stomach, back, and neck with pruritic progression over 24 h. Approximately 4 hours after first appearance of the rash, the patient became febrile (temperature 101.7°F), fatigued, and a headache developed.
Rash spread to the legs and upper arms, continuing to appear flat, mottled, and became pruritic. Fatigue persisted, along with headache with light sensitivity, myalgias (particularly in the back and shoulders), and nausea with anorexia. The patient reported that her eyes were painful to open, but upon examination, the eyes appeared normal with no redness or swelling.
The rash continued to progress to the entire body, but with decreasing pruritus and increasing papular appearance. Conjunctivitis and cervical adenopathy were noted on physician examination, and the patient reported increased myalgias and dysphagia, with development of painful vesicles throughout the oral mucosa.
Fever resolved
Rash and sore throat resolved
Desquamation was noted on palms of both hands and soles of both feet
17 Resolution of all signs and symptoms

Main Article

Page created: December 14, 2016
Page updated: December 14, 2016
Page reviewed: December 14, 2016
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