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Volume 23, Number 10—October 2017
Research Letter

Carbapenemase VCC-1–Producing Vibrio cholerae in Coastal Waters of Germany

Jens A. HammerlComments to Author , Claudia Jäckel, Valeria Bortolaia, Keike Schwartz, Nadja Bier, Rene S. Hendriksen, Beatriz Guerra1, and Eckhard Strauch
Author affiliations: German Federal Institute for Risk Assessment, Berlin, Germany (J.A. Hammerl, C. Jäckel. K. Schwartz, N. Bier, B. Guerra, E. Strauch); Technical University of Denmark, Lyngby, Denmark (V. Bortolaia, R.S. Hendriksen)

Main Article

Table

Genome characteristics of 4 carbapenemase-producing Vibrio cholerae isolates from coastal waters of Germany*

Characteristic Isolate
VN-2808 VN-2825 VN-2923 VN-2997
No. genes 3,934 3,921 4,040 3,933
Coding genes 3,545 3,608 3,650 3,612
No. CDS 3,813 3,803 3,920 3,814
Coding CDS 3,545 3,608 3,650 3,612
No. RNA genes 121 118 120 119
No. rRNAs (5S, 16S, 23S) 10, 12, 7 10, 12, 4 10, 11, 7 10, 12, 4
Complete rRNAs (5S, 23S) 10, 1 10, 1 10, 1 10, 1
Partial rRNAs (16S, 23S) 12, 6 12, 3 11, 6 12, 3
No. tRNAs 88 88 88 89
No. noncoding RNAs 4 4 4 4
No. pseudogenes 268 195 270 202
Ambiguous residues 0 0 0 0
Frameshifted 39 37 40 37
Incomplete 220 144 221 152
Internal stop 20 25 22 23
Multiple problems 11 11 13 10
No. predicted prophages 5 2 5 2
Intact 2 0 1 0
Incomplete 3 1 4 2
Questionable 0 1 0 0
No. plasmids ND ND ND ND
Antibiotic resistance
β-lactam† blaVCC-1 (100%) blaVCC-1 (100%) blaVCC-1 (100%) blaVCC-1 (100%)
MLST type ST336 ST336 ST336 ST336
GenBank information
Bioproject no. PRJNA331077 PRJNA331078 PRJNA331079 PRJNA331080
Biosample no. SAMN05437226 SAMN0537225 SAMN0537224 SAMN0537223
Accession no. MCBB00000000 MCBA00000000 MCAZ00000000 MCAY00000000

*In silico analyses were conducted by using the services of the NCB Prokaryotic Genome Annotation Pipeline (https://www.ncbi.nlm.nih.gov/genome/annotation_prok/), the Center for Genomic Epidemiology (http://.genomicepidemiology.org), and PHAST (http://www.phast.wishartlab.com/).CDS, coding DNA sequence; MLST, multilocus sequencing typing; ND, not determined; ST, sequence type.
†Percentage values indicate level of nucleotide similarity against the reference gene (GenBank accession no. KT818596).

Main Article

1Current affiliation: European Food Safety Authority, Parma, Italy.

Page created: September 19, 2017
Page updated: September 19, 2017
Page reviewed: September 19, 2017
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