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Volume 23, Number 2—February 2017

Research Letter

Emergence of blaNDM-7–Producing Enterobacteriaceae in Gabon, 2016

Mesmin Moussounda, Seydina M. Diene, Sandra Dos Santos, Alain Goudeau, Patrice FrançoisComments to Author , and Nathalie van der Mee-Marquet
Author affiliations: Hôpital d’Instruction des Armées Omar Bongo Ondimba, Libreville, Gabon (M. Moussounda); Centre Hospitalier Régional Universitaire, Tours, France (M. Moussounda, S. Dos Santos, A. Goudeau, N. van der Mee-Marquet); University of Geneva Hospitals, Geneva, Switzerland (S.M. Diene, P. François)

Main Article

Table

Characteristics of blaNDM-7–producing Enterobacteriacae isolates from patients in a military hospital, Gabon, 2016*

Characteristic Isolate
S1 S2 S3 S4
Species Klebsiella pneumoniae K. pneumoniae K. pneumoniae Enterbacter cloacae
No. contigs 83 104 86 61
Genome and plasmid size, bp
 5′688′′217
 5′710′′179
 5′699′′938
 4′860′′761
Resistome genes according to antibiotic class
β-lactams
blaSHV-28 + + +
blaCTX-M-15 + + +
blaNDM-7 + + + +
blaOXA-9 + + +
act-17 +
ampR +
lap-2 +
blaSHV-12 +
blaTEM-104 +
Aminoglycosides
aac6′-Ib + + +
aac3-IIa + + +
ant3 + + +
aac3 +
Sulfamids
folA + + + +
sul1 + + +
sul2 + + + +
dhfr1 + + + +
Others
fosA + + +
arr-ms + + +
tetD + + +
tetA-2 +
qnrS1 +
mphA +
cat +

*aac3, aminoglycoside 3-N-acetyltransferase; aac3-IIa, aminoglycoside N-acetyltransferase AAC(3)-IIa; aac6′-lb-cr, AAC(6′)-Ib-cr family aminoglycoside N(6′)-acetyltransferase; aac6′-Ib, AAC(6′)-Ib family aminoglycoside 6′-N-acetyltransferase; act-7, cephalosporin-hydrolyzing class C β-lactamase ACT-17; ampR, ampicillin chromosomal-mediated β-lactamase; ant3, streptomycin 3′′-adenylyltransferase; arr-ms, rifampin ADP-ribosyl transferase; blaCTX-M-15, class A extended-spectrum β-lactamase CTX-M-15; blaNDM-7, New Delhi metallo-β-lactamase NDM-7; blaOXA-9, oxacillin-hydrolyzing class D β-lactamase OXA-9; blaSHV-12, β-lactamase SHV-12 ; blaSHV-28, class A β-lactamase SHV-28; blaTEM-104, β-lactamase TEM-104; cat, chloramphenicol acetyltransferase; dhfr1, dihydrofolate reductase type 1; folA, dihydrofolate reductase; fosA, fosfomycin resistance glutathione transferase FosA; lap-2, class A β-lactamase LAP-2; qnrS1, quinolone resistance pentapeptide repeat protein QnrS1; mphA, Mph(A) family macrolide 2′-phosphotransferase; sul1, sulfonamide-resistant dihydropteroate synthase Sul1; sul2, sulfonamide-resistant dihydropteroate synthase Sul2; tetA-2, tetracycline resistance protein, class C; tetD, tetracycline efflux MFS transporter Tet(D).

Main Article

Page created: January 18, 2017
Page updated: January 18, 2017
Page reviewed: January 18, 2017
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