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Volume 23, Number 2—February 2017
Dispatch

Biofilm-Forming Capability of Highly Virulent, Multidrug-Resistant Candida auris

Leighann Sherry, Gordon Ramage, Ryan Kean, Andrew Borman, Elizabeth M. Johnson, Malcolm D. Richardson, and Riina Rautemaa-RichardsonComments to Author 
Author affiliations: University of Glasgow, Glasgow, Scotland, UK (L. Sherry, G. Ramage, R. Kean); Public Health England, Bristol, UK (A. Borman, E.M. Johnson); The University of Manchester, Manchester, UK (M.D. Richardson, R. Rautemaa-Richardson); University Hospital of South Manchester, Manchester (M.D. Richardson, R. Rautemaa-Richardson)

Main Article

Table 2

Sessile susceptibility profiles of 7 antifungals against Candida auris yeast

Drug
 Sessile MIC*
Strain 2
 Strain 6
 Strain 10
 Strain 12
Fluconazole >32 >32 >32 >32
Voriconazole >32 >32 >32 >32
Caspofungin >32 >32 >32 >32
Micafungin >32 >32 0.25 >32
Liposomal amphotericin B 2 8 16 16
Amphotericin B 2 4 2 4
Chlorhexidine, % <0.02 <0.02 <0.02 <0.02

*Values are mg/L except as indicated. Sessile MICs are defined as a 90% inhibition of the metabolic dye XTT, 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt (Sigma-Aldrich, Dorset, UK) compared with the untreated control; MIC tests were performed on 3 independent occasions and showed identical results each time.

Main Article

Page created: January 17, 2017
Page updated: January 17, 2017
Page reviewed: January 17, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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