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Volume 23, Number 6—June 2017
Dispatch

Clinical and Molecular Characteristics of Human Rotavirus G8P[8] Outbreak Strain, Japan, 2014

Kenji Kondo, Takeshi TsugawaComments to Author , Mayumi Ono, Toshio Ohara, Shinsuke Fujibayashi, Yasuo Tahara, Noriaki Kubo, Shuji Nakata, Yoshihito Higashidate, Yoshiki Fujii, Hirokazu Kimura, Yuko Yoto, and Hiroyuki Tsutsumi
Author affiliations: Sapporo Medical University School of Medicine, Sapporo, Japan (K. Kondo, T. Tsugawa, M. Ono, Y. Yoto, H. Tsutsumi); Tomakomai City Hospital, Tomakomai, Japan (T. Ohara); Tomakomai Children's Clinic, Tomakomai (S. Fujibayashi); Steel Memorial Muroran Hospital, Muroran, Japan (Y. Tahara); Japanese Red Cross Urakawa Hospital, Urakawa, Japan (N. Kubo); Nakata Pediatric Clinic, Sapporo (S. Nakata); Sapporo Hokushin Hospital, Sapporo (Y. Higashidate); National Institute of Infectious Diseases, Tokyo, Japan (Y. Fujii, K. Katayama)

Main Article

Table 2

Genotype constellations and nucleotide identities of strains closely related to To14-0, the representative G8P[8] rotavirus strain used in a study of the clinical and molecular features of a G8P[8] rotavirus outbreak strain, Hokkaido Prefecture, Japan, 2014

Strain (genotype representative from study/country) Genotype constellations and nucleotide identities (%), by gene*
VP7 VP4 VP6 VP1 VP2 VP3 NSP1 NSP2 NSP3 NSP4 NSP5
Human/To14-0 (G8P[8] in study)
 G8 (100)
 P[8] (100)
 I2 (100)
 R2 (100)
 C2 (100)
 M2 (100)
 A2 (100)
 N2 (100)
 T2 (100)
 E2 (100)
 H2 (100)
Human/VNM/RVN1149/2014/G8P[8] (G8P[8] in Vietnam)
 G8 (99.4)
 P[8] (99.8)
 I2 (99.8)
 R2 (99.6)
 C2 (99.6)
 M2 (99.8)
 A2 (100)
 N2 (99.9)
 T2 (99.5)
 E2 (99.9)
 H2 (99.5)
Human/THA/NP-130/2014/G8P[8] (G8P[8] in Thailand)
 G8 (99.7)
 P[8] (99.9)
 I2 (99.9)
 R2 (99.9)
 C2 (99.8)
 M2 (99.9)
 A2 (99.9)
 N2 (99.7)
 T2 (99.8)
 E2 (99.7)
 H2 (99.5)
Human/THA/KKL-17/2013/G8P[8] (G8P[8] in Thailand)
 G8 (99.5)
 P[8] (99.8)
 I2 (91.5)
 R2 (99.9)
 C2 (99.9)
 M2 (99.9)
 A2 (99.9)
 N2 (99.8)
 T2 (99.9)
 E2 (99.7)
 H2 (99.2)
Human/THA/LS-04/2013/G2P[8] 
(DS-1–like G2P[8] in Thailand)
 G2
(–)
 P[8] (99.8)
 I2 (99.5)
 R2 (86.0)
 C2 (99.8)
 M2 (97.4)
 A2 (99.9)
 N2 (99.8)
 T2 (98.6)
 E2 (95.5)
 H2 (99.7)
Human/THA/SKT-109/2013/G1P[8] (DS-1–like G1P[8] in Thailand)
 G1
(–)
 P[8] (99.7)
 I2 (98.7)
 R2 (86.1)
 C2 (99.9)
 M2 (99.8)
 A2 (99.8)
 N2 (85.8)
 T2 (99.8)
 E2 (94.5)
 H2 (99.2)
Human/To14-41 (DS-1–like G1P[8] in study)
 G1
(–)
 P[8] (98.8)
 I2 (98.3)
 R2 (86.3)
 C2 (99.4)
 M2 (99.4)
 A2 (99.5)
 N2 (85.5)
 T2 (99.6)
 E2 (93.5)
 H2 (98.8)
Human/JPN/NT004/2012/G1P[8] 
(DS-1–like G1P[8] in Japan)
 G1
(–)
 P[8] (99.0)
 I2 (98.4)
 R2 (86.3)
 C2 (99.7)
 M2 (99.5)
 A2 (99.5)
 N2 (85.6)
 T2 (99.6)
 E2 (94.5)
 H2 (99.2)
Human/THA/NP-M51/2013/G2P[4] (G2P[4] in Thailand)
 G2
(–)
 P[4]
(–)
 I2 (99.5)
 R2 (86.0)
 C2 (99.1)
 M2 (97.5)
 A2 (99.0)
 N2 (85.4)
 T2 (98.7)
 E2 (95.5)
 H2 (99.7)
Human/KOR/CAU15–11/2015/G2P[4] (G2P[4] in South Korea)
 G2
(–)
 P[4]
(–)
 I2 (99.5)
 R2 (85.9)
 C2 (99.2)
 M2 (97.4)
 A2 (94.0)
 N2 (84.8)
 T2 (98.1)
 E2 (95.3)
 H2 (98.6)
Human/MU14114 (G2P[4] in study)
 G2
(–)
 P[4]
(–)
 I2 (97.0)
 R2 (85.3)
 C2 (96.9)
 M2 (86.4)
 A2 (95.8)
 N2 (85.5)
 T2 (96.7)
 E2 (95.6)
 H2 (98.3)
Human/ITA/PR457/2009/G10P[14]
 G10
(–)
 P[14]
(–)
 I2 (93.0)
 R2 (98.1)
 C2 (82.3)
 M2 (86.6)
 A11
(–)
 N2 (86.4)
 T6
(–)
 E2 (94.3)
 H3
(–)
Caprine/BGL/GO34/1999/G6P[1]
 G6
(–)
 P[1]
(–)
 I2 (94.9)
 R2 (86.3)
 C2 (83.4)
 M2 (86.8)
 A11
(–)
 N2 (86.6)
 T6
(–)
 E2 (96.0)
 H3
(–)
Human/COD/DRC88/2003/G8P[8] (G8P[8] in Africa)
 G8 (86.0)
 P[8] (98.3)
 I2 (96.3)
 R2 (85.6)
 C2 (97.4)
 M2 (97.0)
 A2 (96.4)
 N2 (85.8)
 T2 (97.1)
 E2 (90.1)
 H2 (97.4)
Human/MWI/QEC287/2006/G8P[8] (G8P[8] in Africa)
 G8 (85.5)
 P[8] (98.3)
 I2 (96.3)
 R2 (85.6)
 C2 (97.8)
 M2 (96.0)
 A2 (96.5)
 N2 (86.9)
 T2 (96.6)
 E2 (89.2)
 H2 (97.6)
Human/MWI/QEC289/2006/G8P[8] (G8P[8] in Africa) G8 (85.5) P[8] (97.5) I2 (96.3) R2 (85.5) C2 (97.8) M2 (95.9) A2 (96.5) N2 (86.9) T2 (96.6) E2 (89.2) H2 (97.6)

*Purple indicates G8 genotype; green indicates Wa-like genome segments; red indicates DS-1–like genome segments; bold indicates nucleotide identities >99.0%; – indicates percentages not calculated because the genotype was different that for To14-0.

Main Article

Page created: May 16, 2017
Page updated: May 16, 2017
Page reviewed: May 16, 2017
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