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Volume 23, Number 6—June 2017

Dispatch

Severe Neurologic Disorders in 2 Fetuses with Zika Virus Infection, Colombia

Jorge Acosta-ReyesComments to Author , Edgar Navarro, Maria José Herrera, Eloina Goenaga, Martha L. Ospina, Edgar Parra, Marcela Mercado, Pablo Chaparro, Mauricio Beltran, Maria Luz Gunturiz, Lissethe Pardo, Catalina Valencia, Sandra Huertas, Jorge Rodríguez, Germán Ruiz, Diana Valencia, Lisa B. Haddad, Sarah C. Tinker, Cynthia A. Moore, and Hernando Baquero
Author affiliations: Universidad del Norte, Barranquilla, Colombia (J. Acosta-Reyes, E. Navarro, M.J. Herrera, H. Baquero); Secretaría de Salud de Barranquilla, Barranquilla (E. Goenaga); Instituto Nacional de Salud, Bogotá, Colombia (M.L. Ospina, E. Parra, M. Mercado, P. Chaparro, M. Beltrán, M.L. Gunturiz, L. Pardo); Clínica Colsanitas, Clínica Reina Sofía, Bogotá (C. Valencia, S. Huertas, J. Rodríguez, G. Ruiz); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (D. Valencia, S.C. Tinker, C.A. Moore); Emory University School of Medicine, Atlanta (L.B. Haddad).

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Figure 1

Pathology findings for case 1, involving a fetus examined after pregnancy termination who had severe neurologic defects attributed to maternal Zika virus infection, Colombia. A) Remnant tissue of cerebral cortex showing a reduced neuroblast layer (dotted lines) and hemorrhagic foci (arrow). Hematoxylin and eosin (H&E) staining; original magnification ×40. B) Glial leptomeningeal heterotopy showing congestive blood vessels (arrowhead) and foci of glial heterotopia (arrows). H&E staining;

Figure 1. Pathology findings for case 1, involving a fetus examined after pregnancy termination who had severe neurologic defects attributed to maternal Zika virus infection, Colombia. A) Remnant tissue of cerebral cortex showing a reduced neuroblast layer (dotted lines) and hemorrhagic foci (arrow). Hematoxylin and eosin (H&E) staining; original magnification ×40. B) Glial leptomeningeal heterotopy showing congestive blood vessels (arrowhead) and foci of glial heterotopia (arrows). H&E staining; original magnification ×10. C) Glial leptomeningeal heterotopy showing congestive blood vessels (arrowhead) and foci of glial heterotopia (arrows). H&E staining; original magnification ×40.

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