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Volume 23, Number 6—June 2017

Dispatch

Severe Neurologic Disorders in 2 Fetuses with Zika Virus Infection, Colombia

Jorge Acosta-ReyesComments to Author , Edgar Navarro, Maria José Herrera, Eloina Goenaga, Martha L. Ospina, Edgar Parra, Marcela Mercado, Pablo Chaparro, Mauricio Beltran, Maria Luz Gunturiz, Lissethe Pardo, Catalina Valencia, Sandra Huertas, Jorge Rodríguez, Germán Ruiz, Diana Valencia, Lisa B. Haddad, Sarah C. Tinker, Cynthia A. Moore, and Hernando Baquero
Author affiliations: Universidad del Norte, Barranquilla, Colombia (J. Acosta-Reyes, E. Navarro, M.J. Herrera, H. Baquero); Secretaría de Salud de Barranquilla, Barranquilla (E. Goenaga); Instituto Nacional de Salud, Bogotá, Colombia (M.L. Ospina, E. Parra, M. Mercado, P. Chaparro, M. Beltrán, M.L. Gunturiz, L. Pardo); Clínica Colsanitas, Clínica Reina Sofía, Bogotá (C. Valencia, S. Huertas, J. Rodríguez, G. Ruiz); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (D. Valencia, S.C. Tinker, C.A. Moore); Emory University School of Medicine, Atlanta (L.B. Haddad).

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Figure 2

Pathology findings for case 2, involving a fetus examined after pregnancy termination who had severe neurologic defects attributed to maternal Zika virus infection, Colombia. A) Spinal cord slice showing neuropil disruption with multiple calcifications (arrowheads). B) Nerve showing disruptive changes of axons (Wallerian degeneration) (black star). C) Dorsal root ganglion showing spinal ganglion with satellitosis (arrow) and neuronophagia of ganglion cells (arrowhead). Hematoxylin and eosin stai

Figure 2. Pathology findings for case 2, involving a fetus examined after pregnancy termination who had severe neurologic defects attributed to maternal Zika virus infection, Colombia. A) Spinal cord slice showing neuropil disruption with multiple calcifications (arrowheads). B) Nerve showing disruptive changes of axons (Wallerian degeneration) (black star). C) Dorsal root ganglion showing spinal ganglion with satellitosis (arrow) and neuronophagia of ganglion cells (arrowhead). Hematoxylin and eosin staining; original magnification ×100.

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