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Volume 23, Number 6—June 2017

Dispatch

Domestic Pig Unlikely Reservoir for MERS-CoV

Emmie de Wit, Friederike Feldmann, Eva Horne, Cynthia Martellaro, Elaine Haddock, Trenton Bushmaker, Kyle Rosenke, Atsushi Okumura, Rebecca Rosenke, Greg Saturday, Dana Scott, and Heinz FeldmannComments to Author 
Author affiliations: National Institutes of Health, Hamilton, Montana, USA (E. de Wit, F. Feldmann, E. Horne, C. Martellaro, E. Haddock, T. Bushmaker, K. Rosenke, R. Rosenke, G. Saturday, D. Scott, H. Feldmann); Columbia University, New York, New York, USA (A. Okumura)

Main Article

Table

Comparison of the amino acid residues shown to be essential in binding of Middle East respiratory syndrome coronavirus spike protein to DPP4 of human, dromedary camel, and domestic pig*

Species
DPP4, aa position
229
267
286
288
291
294
295
298
317
322
336
341
344
346
Human†
N
K
Q
T
A
L
I
H
R
Y
R
V
Q
I
Dromedary camel‡



V










Domestic pig§



V










Mouse¶ P A R T S V

* DPP4, dipeptidyl peptidase 4; –, no change from human DPP4.
†GenBank accession no. AB451339.
‡GenBank accession no. KF574263.
§GenBank accession no. NM214257.
¶Taken from previous publication (7).

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