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Volume 23, Number 8—August 2017
Research

Molecular Characterization of Corynebacterium diphtheriae Outbreak Isolates, South Africa, March–June 2015

Mignon du PlessisComments to Author , Nicole Wolter, Mushal Allam, Linda de Gouveia, Fahima Moosa, Genevie Ntshoe, Lucille Blumberg, Cheryl Cohen, Marshagne Smith, Portia Mutevedzi, Juno Thomas, Valentino Horne, Prashini Moodley, Moherndran Archary, Yesholata Mahabeer, Saajida Mahomed, Warren Kuhn, Koleka Mlisana, Kerrigan McCarthy, and Anne von Gottberg
Author affiliations: National Health Laboratory Service, Johannesburg, South Africa (M. du Plessis, N. Wolter, M. Allam, L. de Gouveia, F. Moosa, G. Ntshoe, L. Blumberg, C. Cohen, M. Smith, P. Mutevedzi, J. Thomas, K. McCarthy, A. von Gottberg); University of the Witwatersrand, Johannesburg (M. du Plessis, N. Wolter, C. Cohen, A. von Gottberg); National Health Laboratory Service, Cape Town, South Africa (V. Horne); University of KwaZulu-Natal, Durban, South Africa (P. Moodley, M. Archary, Y. Mahabeer, S. Mahomed, W. Kuhn, K. Mlisana); National Health Laboratory Service, Durban (Y. Mahabeer, K. Mlisana); National Department of Health, KwaZulu-Natal, South Africa (W. Kuhn)

Main Article

Table 1

Corynebacterium controls and nonoutbreak–associated C. diphtheriae isolates from South Africa*

Isolate no. Organism (biotype) Toxin-producing ST
ATCC 13812 (PW8) C. diphtheriae (gravis) Yes 44
NCTC 10648 C. diphtheriae (gravis) Yes 25
NCTC 10356 C. diphtheriae (belfanti) No 106
NCTC 3984 C. diphtheriae (gravis) Yes 10
NCTC 5011 C. diphtheriae (intermedius) Yes 143
NCTC 13129† C. diphtheriae (gravis) Yes 8
NCTC 12077 C. ulcerans No NA
ATCC 7715 C. bovis No NA
ATCC BAA-1293 C. striatum No NA
6853‡ C. diphtheriae No 395
2337‡ C. diphtheriae No 402
46403§ C. diphtheriae No 391
46337§ C. diphtheriae No 390

*ATCC, American Type Culture Collection; NA, not applicable; NCTC, National Collection of Type Cultures; ST, sequence type.
†Clinical isolate from a 72-year-old woman in the United Kingdom isolated following her return from a Baltic cruise in 1997. This isolate is representative of the Russia outbreak clone (17).
‡Historical clinical isolates from South Africa ca. 1980s. No clinical information is available for these isolates.
§Clinical isolates from 8-year-old (46403) and 9-year-old (46337) endocarditis patients from the Western Cape Province of South Africa, July–August 2015.

Main Article

Page created: July 17, 2017
Page updated: July 17, 2017
Page reviewed: July 17, 2017
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