Volume 23, Number 9—September 2017
Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion
|Recipient and CWD
||PrP-res+||Incubation period, d
|H95/wt||7||5||2||669, 671, 706, 706, 706|
|H95/S96||7||7||0||306, 593, 593, 593, 593, 673, 675|
|wt/wt||8||3||5||652, 653, 653|
*Mice infected with CWD prions were observed for up to 708 d; hamsters infected with white-tailed deer and elk CWD prions were observed for 659 and 726 d, respectively. Control mice and hamsters were inoculated with brain homogenates from CWD-negative wt/wt deer. CWD, chronic wasting disease; NA, not applicable; PrP-res+, positive for proteinase-K–resistant prion protein; wt, wild type.
1These authors contributed equally to this article.