Volume 24, Number 1—January 2018
CME ACTIVITY - Synopsis
Zika Virus Testing and Outcomes during Pregnancy, Florida, USA, 2016
Colette Shiu1, Rebecca Starker1, Jaclyn Kwal, Michelle Bartlett, Anise Crane, Samantha Greissman, Naiomi Gunaratne, Meghan Lardy, Michelle Picon, Patricia Rodriguez, Ivan Gonzalez, and Christine L. Curry
Table 5
Clinical and laboratory characteristics of 2 infants and their mothers who had laboratory evidence of Zika virus infection, Miami–Dade County, Florida, USA, 2016*
| Characteristic | Case-infant 1 | Case-infant 2 |
|---|---|---|
| Country of exposure | Haiti | Venezuela |
| Gestational age at time of symptoms |
≈10 wk (2015 Nov) |
≈12 wk (2015 Dec) |
| Laboratory results for Zika virus | ||
| Mother | Serum IgM neg (April 2016) | Serum neg rRT-PCR, pos IgM (2016 Apr) |
| Infant |
Serum/CSF neg rRT-PCR, pos IgM, pos PRNT >10 Zika virus (2016 May) |
Serum/CSF/CB neg rRT-PCR, pos IgM (2016 Jun) |
| Antenatal ultrasound | HC <3%, BPD <3% (33.1 WGA) | HC 10%, BPD 34% (36.4 WGA) |
| HC at birth |
30.5 cm (<1%) |
34 cm (25%–50%) |
| Postnatal cranial imaging |
Serpiginous calcifications, R; polymicrogyriccortex, BL; simplified gyral pattern (BL, L >R) |
Linear calcifications, L; polymicrogyric cortex, R; atrophy cerebral peduncle, R; overall volume loss of entire brain, R >L |
| Ocular evaluation | Unremarkable | Hypopigmented R superior retinal lesion |
| Auditory evaluation | Unremarkable | Normal |
*BL, bilateral ; BPD, biparietal diameter; CSF, cerebrospinal fluid; HC, head circumference; L, left; neg, negative; pos, positive; PRNT, plague-reduction neutralization test; R, right; rRT-PCR, real-time reverse transcription PCR; WGA, weeks gestational age.
1These authors contributed equally to this article.
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