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Volume 24, Number 1—January 2018

Zika Virus Testing and Outcomes during Pregnancy, Florida, USA, 2016

Colette Shiu1, Rebecca Starker1, Jaclyn Kwal, Michelle Bartlett, Anise Crane, Samantha Greissman, Naiomi Gunaratne, Meghan Lardy, Michelle Picon, Patricia Rodriguez, Ivan Gonzalez, and Christine L. CurryComments to Author 
Author affiliations: University of Miami Miller School of Medicine, Miami, Florida, USA (C. Shiu, R. Starker, J. Kwal, M. Bartlett, A. Crane, S. Greissman, N. Gunaratne, M. Lardy, M. Picon, P. Rodriguez, I. Gonzalez, C.L. Curry); Jackson Memorial Hospital, Miami (P. Rodriguez, I. Gonzalez, C.L. Curry)

Main Article

Table 5

Clinical and laboratory characteristics of 2 infants and their mothers who had laboratory evidence of Zika virus infection, Miami–Dade County, Florida, USA, 2016*

Characteristic Case-infant 1 Case-infant 2
Country of exposure Haiti Venezuela
Gestational age at time of symptoms
≈10 wk (2015 Nov)
≈12 wk (2015 Dec)
Laboratory results for Zika virus
Mother Serum IgM neg (April 2016) Serum neg rRT-PCR, pos IgM (2016 Apr)
Serum/CSF neg rRT-PCR, pos IgM, pos PRNT >10 Zika virus (2016 May)
Serum/CSF/CB neg rRT-PCR, pos IgM (2016 Jun)
Antenatal ultrasound HC <3%, BPD <3% (33.1 WGA) HC 10%, BPD 34% (36.4 WGA)
HC at birth
30.5 cm (<1%)
34 cm (25%–50%)
Postnatal cranial imaging
Serpiginous calcifications, R; polymicrogyriccortex, BL; simplified gyral pattern (BL, L >R)
Linear calcifications, L; polymicrogyric cortex, R; atrophy cerebral peduncle, R; overall volume loss of entire brain, R >L
Ocular evaluation Unremarkable Hypopigmented R superior retinal lesion
Auditory evaluation Unremarkable Normal

*BL, bilateral ; BPD, biparietal diameter; CSF, cerebrospinal fluid; HC, head circumference; L, left; neg, negative; pos, positive; PRNT, plague-reduction neutralization test; R, right; rRT-PCR, real-time reverse transcription PCR; WGA, weeks gestational age.

Main Article

1These authors contributed equally to this article.

Page created: December 18, 2017
Page updated: December 18, 2017
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