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Volume 24, Number 1—January 2018
Dispatch

Mammalian Pathogenesis and Transmission of Avian Influenza A(H7N9) Viruses, Tennessee, USA, 2017

Jessica A. Belser, Nicole Brock, Xiangjie Sun, Joyce Jones, Natosha Zanders, Erin Hodges, Joanna A. Pulit-Penaloza, David Wentworth, Terrence M. Tumpey, Todd Davis, and Taronna R. MainesComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Figure 1

Transmission of avian influenza A(H7N9) influenza virus ck/TN by direct contact, Tennessee, USA, 2017. Three ferrets were inoculated with 106 EID50 of A) low pathogenicity avian influenza virus or B) highly pathogenic avian influenza virus, and nasal washes were collected from each ferret on the indicated days pi (left bars) to assess viral replication. An immunologically naive ferret (gray bars) was placed in the same cage as each inoculated ferret at 24 h pi, and nasal washes were collected fr

Figure 1. Transmission of avian influenza A(H7N9) virus ck/TN between ferrets in direct contact, Tennessee, USA, 2017. Three ferrets were inoculated with 106 EID50 of A) low pathogenicity avian influenza virus or B) highly pathogenic avian influenza virus, and nasal washes were collected from each ferret on the indicated days postinoculation (left bars) to assess viral replication. An immunologically naive ferret was placed in the same cage as each inoculated ferret at 24 h postinoculation, and nasal washes were collected from each contact ferret on the indicated days postcontact. Bars indicate individual ferrets. All ferrets were serologically negative for circulating influenza viruses at the start of the study. The limit of virus detection was 101.5 EID50/mL. EID50, 50% egg infectious dose.

Main Article

Page created: December 19, 2017
Page updated: December 19, 2017
Page reviewed: December 19, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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