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Volume 24, Number 10—October 2018

Mycobacterium caprae Infection in Captive Borneo Elephant, Japan

Shiomi YoshidaComments to Author , Satomi Suga, Satoshi Ishikawa, Yasuhiko Mukai, Kazunari Tsuyuguchi, Yoshikazu Inoue, Taro Yamamoto, and Takayuki Wada
Author affiliations: Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan (S. Yoshida); National Hospital Organization Kinki-chuo Chest Medical Center Clinical Research Center, Sakai, Japan (S. Yoshida, K. Tsuyuguchi, Y. Inoue); Fukuyama Zoo, Fukuyama, Japan (S. Suga, S. Ishikawa, Y. Mukai); Nagasaki University Institute of Tropical Medicine, Nagasaki (T. Yamamoto, T. Wada); Nagasaki University School of Tropical Medicine and Global Health, Nagasaki (T. Wada)

Main Article

Table 2

Single-nucleotide polymorphism differences between isolates EPDC01 and EPDC02 from a captive Borneo elephant with Mycobacterium caprae infection, Japan, 2016*

Genomic position Gene Mutation Amino acid change Description of function
1,338,135 Rv1194c G → frameshift Gln127 → frameshift Unknown
1,445,272 Rv1290A C → T Ala72 → Val Unknown
2,155,168 katG C → T Ser315 → Asn Catalase; isoniazid resistance
2,577,556 Rv2306A G → A Gly150 → Glu Unknown
3,200,585 Rv2891 T → G Leu107 → Arg Unknown
3,777,062 Rv3365c C → A Gly147 → Val Unknown
4,298,329 pks2 G → A Pro426 → Leu Lipid metabolism
4,345,372 Rv3869 G → C Ala112 → Pro Unknown

*Excluded paralogue genes, which are the descendants of an ancestral gene and underwent a duplication event.

Main Article

Page created: September 16, 2018
Page updated: September 16, 2018
Page reviewed: September 16, 2018
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