Skip directly to page options Skip directly to A-Z link
Volume 24, Number 10—October 2018
Dispatch

Effectiveness of Whole, Inactivated, Low Pathogenicity Influenza A(H7N9) Vaccine against Antigenically Distinct, Highly Pathogenic H7N9 Virus

Masato Hatta, Gongxun Zhong, Shiho Chiba, Tiago J.S. Lopes, Gabriele Neumann, and Yoshihiro KawaokaComments to Author 
Author affiliations: University of Wisconsin–Madison, Madison, Wisconsin, USA (M. Hatta, G. Zhong, S. Chiba, T.J.S. Lopes, G. Neumann, Y. Kawaoka); University of Tokyo, Tokyo, Japan (Y. Kawaoka)

Main Article

Figure 2

Virus titers in throat and nasal swab specimens and in the organs of vaccinated and nonvaccinated ferrets challenged with highly pathogenic influenza A(H7N9) virus. A) Virus titers in swab samples. Throat and nasal swabs were collected on days 1–7 postchallenge. Virus titers were determined based on plaque assays in MDCK cells. Statistical significance was determined as described in the Technical Appendix. B) Three ferrets from each group were euthanized on day 4 postchallenge for virus titratio

Figure 2. Virus titers in throat and nasal swab specimens and in the organs of vaccinated and nonvaccinated ferrets challenged with highly pathogenic influenza A(H7N9) virus. A) Virus titers in swab samples. Throat and nasal swabs were collected on days 1–7 postchallenge. Virus titers were determined based on plaque assays in MDCK cells. Statistical significance was determined as described in the Technical Appendix. B) Three ferrets from each group were euthanized on day 4 postchallenge for virus titration in the indicated organs. We also assessed virus titers in organs of ferrets that were euthanized because of severe symptoms (*). Virus titers were determined based on plaque assays in MDCK cells. Numbers along baseline indicate animal number. PBS, phosphate-buffered saline.

Download

Main Article

Page created: September 16, 2018
Page updated: September 16, 2018
Page reviewed: September 16, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external