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Volume 24, Number 10—October 2018
Research

Candida auris in Healthcare Facilities, New York, USA, 2013–2017

Eleanor Adams, Monica Quinn, Sharon Tsay, Eugenie Poirot, Sudha Chaturvedi, Karen Southwick, Jane Greenko, Rafael Fernandez, Alex Kallen, Snigdha Vallabhaneni, Valerie Haley, Brad Hutton, Debra Blog, Emily LutterlohComments to Author , Howard Zucker, and Candida auris Investigation Workgroup1
Author affiliations: New York State Department of Health, New Rochelle, New York, USA (E. Adams, K. Southwick); New York State Department of Health, Albany, New York, USA (M. Quinn, S. Chaturvedi, V. Haley, B. Hutton, D. Blog, E. Lutterloh, H. Zucker); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S. Tsay, E. Poirot, A. Kallen, S. Vallabhaneni); New York City Department of Health and Mental Hygiene, New York, New York, USA (E. Poirot); New York State Department of Health, Central Islip, New York, USA (J. Greenko); New York State Department of Health, New York (R. Fernandez); State University at Albany School of Public Health, Albany, New York, USA (V. Haley, D. Blog, E. Lutterloh)

Main Article

Table 4

Antifungal susceptibility data for first Candida auris isolates from 51 clinical cases, New York, USA, 2013–2017*

Antifungal Tentative resistance breakpoint (16) MIC50† MIC range† No. (%) resistant
Fluconazole >32 >256 8.00 to >256 50 (98)
Itraconazole NA 0.500 0.25–1.00 NA
Voriconazole NA 2.000 0.50–4.00 NA
Posaconazole NA 0.250 0.12–0.50 NA
Isavuconazole NA 0.500 0.25–2.00 NA
Caspofungin >2 0.060 0.03–0.25 0
Micafungin >4 0.120 0.06–0.25 0
Anidulafungin >4 0.250 0.12–0.50 0
Amphotericin B >2 1.500 0.50–4.00 15 (29)
Flucytosine NA 0.125 0.125–0.25 NA

*NA, not available.
†MICs for azoles and echinocandins are defined as the lowest drug concentration that caused 50% growth inhibition compared with the drug-free controls; MICs for amphotericin B and flucytosine are defined as the lowest concentration at which there was 100% growth inhibition. MIC50 was defined as the MIC at which >50% of the isolates of C. auris tested were inhibited.

Main Article

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1Additional members of the workgroup are listed at the end of this article.

Page created: September 12, 2018
Page updated: September 12, 2018
Page reviewed: September 12, 2018
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