Volume 24, Number 10—October 2018
Research Letter
Molecular Typing and Antifungal Susceptibility of Candida viswanathii, India
Shamanth A. Shankarnarayan, Shivaprakash M. Rudramurthy, Arunaloke Chakrabarti, Dipika Shaw, Saikat Paul, Nandini Sethuraman, Harsimran Kaur, and Anup K. Ghosh
Table
In vitro antifungal susceptibility data of Candida viswanathii isolates from a tertiary care hospital in Chandigarh, India
| Isolate | Antifungal agent | MIC, μg/mL |
|||
|---|---|---|---|---|---|
| Range | MIC 50 | MIC 90 | Geometric mean | ||
| C. viswanathii 2013–2014, n = 7 | Amphotericin B | 0.03–0.25 | 0.25 | 0.25 | 0.16 |
| Itraconazole | 0.03–0.5 | 0.125 | 0.25 | 0.09 | |
| Fluconazole | 0.125–1 | 1 | 1 | 0.41 | |
| Voriconazole | 0.03–0.5 | 0.5 | 0.5 | 0.14 | |
| Micafungin | 0.125 | 0.125 | 0.125 | 0.125 | |
| Caspofungin | 0.5 | 0.5 | 0.5 | 0.5 | |
| Anidulafungin | 0.5–1 | 0.5 | 1 | 0.67 | |
| Posaconazole |
0.0312–0.0625 |
0.0312 |
0.0625 |
0.03 |
|
| C. viswanathii 2015, n = 16 | Amphotericin B | 0.06–0.25 | 0.125 | 0.25 | 0.14 |
| Itraconazole | 0.03–1 | 0.25 | 0.25 | 0.12 | |
| Fluconazole | 0.5–64 | 64 | 64 | 29.34 | |
| Voriconazole | 0.03–8 | 1 | 2 | 0.76 | |
| Micafungin | 0.125 | 0.125 | 0.125 | 0.12 | |
| Caspofungin | 0.125–1 | 0.5 | 0.5 | 0.40 | |
| Anidulafungin | 0.125–1 | 0.5 | 1 | 0.52 | |
| Posaconazole | 0.0321–0.5 | 0.25 | 0.25 | 0.17 | |
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