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Volume 24, Number 11—November 2018
Research Letter

Novel Multidrug-Resistant Cronobacter sakazakii Causing Meningitis in Neonate, China, 2015

Haiyan Zeng1, Tao Lei1, Wenjing He1, Jumei Zhang, Bingshao Liang, Chengsi Li, Na Ling, Yu Ding, Shi Wu, Juan Wang, and Qingping WuComments to Author 
Author affiliations: Guangdong Institute of Microbiology, Guangzhou, China (H. Zeng, T. Lei, W. He, J. Zhang, C. Li, N. Ling, S. Wu, Q. Wu); Guangzhou Women and Children’s Medical Center, Guangzhou (B. Liang); Jinan University, Guangzhou (Y. Ding); South China Agricultural University, Guangzhou (J. Wang)

Main Article

Figure

Analysis of resistance plasmid pGW1 in Cronobacter sakazakii sequence type 256, isolated from neonate with meningitis, China, 2015, showing genetic organization of major drug-resistance determinants in pGW1, along with its structural comparison with that of p505108-MDR. The blaDHA-1 region (A) and multidrug-resistance region (B) of plasmid pGW1 are compared with those of plasmid p505108-MDR, unitig_2, or both. Black indicates genes encoding transposase, light gray indicates genes encoding integr

Figure. Analysis of resistance plasmid pGW1 in Cronobacter sakazakii sequence type 256, isolated from neonate with meningitis, China, 2015, showing genetic organization of major drug-resistance determinants in pGW1, along with its structural comparison with that of p505108-MDR. The blaDHA-1 region (A) and multidrug-resistance region (B) of plasmid pGW1 are compared with those of plasmid p505108-MDR, unitig_2, or both. Black indicates genes encoding transposase, light gray indicates genes encoding integrase, dark gray indicates genes encoding drug resistance, and white indicates other genes. A few hypothetical genes with nucleotide sequences <200 bp are not shown. Shading denotes regions of homology (>95% nt identity); light gray shading indicates same orientation, and dark gray shading indicates reverse orientation. Numbers indicate nucleotide positions within the corresponding plasmids.

Main Article

1These authors contributed equally to this article.

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