Volume 24, Number 12—December 2018
CME ACTIVITY - Research
Substance Use and Adherence to HIV Preexposure Prophylaxis for Men Who Have Sex with Men1
, Sonia Jain, David Moore, Deborah Collins, Xiaoying Sun, Peter L. Anderson, Katya Corado, Jill S. Blumenthal, Eric S. Daar, Joel Milam, Michael P. Dubé, Sheldon Morris, and for the California Collaborative Treatment Group 595 Team
Table 1
Baseline demographic characteristics by substance use status used for assessing substance use and adherence to HIV preexposure prophylaxis among MSM and transgender women, California, USA*
| Characteristic |
Overall, n = 394 |
Substance use |
p value |
||
|---|---|---|---|---|---|
| None, n = 102 |
Some, n = 144 |
Frequent, n = 148 |
|||
| Sex | 0.191 | ||||
| M | 391 (99) | 100 (98) | 143 (99) | 148 (100) | |
| F | 3 (1) | 2 (2) | 1 (1) | 0 | |
| Median age, y (IQR) | 33 (28–41) | 33 (29–40) | 33 (28–41) | 33.5 (28–42) | 0.885 |
| Race, n = 386† | 0.238 | ||||
| Asian | 12 (3) | 2 (2) | 5 (4) | 5 (3) | |
| Black | 51 (13) | 20 (20) | 19 (13) | 12 (8) | |
| White | 292 (76) | 72 (72) | 104 (73) | 116 (81) | |
| Multiple | 24 (6) | 6 (6) | 10 (7) | 8 (6) | |
| Other | 7 (2) | 0 | 4 (3) | 3 (2) | |
| Hispanic ethnicity, n = 391† | 119 (30) | 30 (29) | 54 (38) | 35 (24) | 0.048 |
| English primary language | 3,786 (95) | 98 (96) | 133 (92) | 145 (98) | 0.066 |
| Education | 0.296 | ||||
| High school or less | 35 (9) | 12 (12) | 15 (10) | 8 (5) | |
| Some college | 146 (37) | 36 (35) | 58 (40) | 52 (35) | |
| Bachelor’s degree | 132 (33) | 31 (30) | 42 (29) | 59 (40) | |
| Postgraduate or advanced degree | 81 (21) | 23 (23) | 29 (20) | 29 (20) | |
| Household income/mo | 0.434 | ||||
| <$2,000 | 84 (21) | 27 (26) | 31 (22) | 26 (18) | |
| >$2,000 | 248 (63) | 63 (62) | 89 (62) | 96 (65) | |
| Not known | 62 (16) | 12 (12) | 24 (17) | 26 (18) | |
| Randomization arm | 0.019 | ||||
| Standard of care | 196 (50) | 60 (59) | 75 (52) | 61 (41) | |
| Text messaging | 198 (50) | 42 (41) | 69 (48) | 87 (59) | |
| Study site | 0.660 | ||||
| Harbor-UCLA | 48 (12) | 11 (11) | 15 (10) | 22 (15) | |
| Long Beach | 46 (12) | 15 (15) | 17 (12) | 14 (9) | |
| UCSD | 173 (44) | 48 (47) | 62 (43) | 63 (43) | |
| USC | 127 (32) | 28 (27) | 50 (35) | 49 (33) | |
| Median PHQ9 for depression (IQR) | 3 (1–7) | 2 (0–5) | 3.5 (1–7) | 5 (2–8) | <0.001 |
| Median baseline DAST10, (IQR) | 2 (0–3) | 0 (0–1) | 2 (1–3) | 3 (2–4) | <0.001 |
*Values are no. (%) unless otherwise noted. DAST, Drug Abuse Screening Test; IQR, interquartile range; MSM, men who have sex with men; PHQ, Patient Health Questionnaire; UCLA, University of California Los Angeles; UCSD, University of California San Diego; USC, University of Southern California.
†Characteristics were not available for all study participants.
1Original data from this study were presented in part at the 2017 Conference on Retroviruses and Opportunistic Infections, February 13–16, 2017, Seattle, Washington, USA; and at the 12th International Conference on HIV Treatment and Prevention Adherence, June 4–6, 2017, Miami, Florida, USA.