Volume 24, Number 12—December 2018
Research
Highly Pathogenic Clone of Shiga Toxin–Producing Escherichia coli O157:H7, England and Wales
Lisa Byrne1, Timothy J. Dallman1, Natalie Adams, Amy F.W. Mikhail, Noel McCarthy, and Claire Jenkins
Table 1
Clinical features of cases of Shiga toxin–producing Escherichia coli O157:H7 belonging to the IIb 250 SNP single linkage cluster 18.% by stx subtype clone, England and Wales, July 2015–December 2017
| stx subtype | No. patients | Diarrhea |
Bloody diarrhea† |
Vomiting |
Hospitalization‡ |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. patients | % Patients (95% CI) | No. patients | % Patients (95% CI) | No. patients | % Patients (95% CI) | No. patients | % Patients (95% CI) | |||||
| stx2c | 36 | 31 | 86.1 (74.2–98.0) | 7 | 22.6 (5.9–33.0) | 10 | 32.3 (12.4–43.1) | 3 | 8.3 (−1.1 to 17.8) | |||
| stx-negative | 77 | 72 | 93.5 (87.8–99.1) | 12 | 16.7 (7.3–23.9) | 23 | 31.9 (19.4–40.3) | 9 | 11.7 (4.3–19.0) | |||
| stx2a |
138 |
127 |
92.0
(87.4–96.6) |
69 |
54.3
(41.5–58.4) |
38 |
29.9
(20.0–35.1) |
35 |
25.4
(18.0–32.7) |
|||
| Total | 251 | 230 | 91.6 (88.1–95.1) | 88 | 38.3 (29.1–41.0) | 71 | 30.9 (22.7–33.9) | 47 | 18.7 (13.9–23.5) | |||
*SNP, single-nucleotide polymorphism.
†Statistically significant difference in reporting by stx subtype using Fisher exact test (p<0.001)
‡Statistically significant difference in reporting by stx subtype using Fisher exact test (p = 0.011)
1These first authors contributed equally to this article.
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