Volume 24, Number 12—December 2018
Research
Highly Pathogenic Clone of Shiga Toxin–Producing Escherichia coli O157:H7, England and Wales
Table 2
Univariable and multivariable logistic regression analysis for reported bloody diarrhea in cases of Shiga toxin–producing Escherichia coli O157:H7 belonging to the IIb, 250 SNP single linkage cluster 18.% by stx subtype clone, England and Wales, July 2015–December 2017*
Exposure | No. (%) patients with bloody diarrhea | No. (%) patients without bloody diarrhea | |||||
---|---|---|---|---|---|---|---|
Univariable analysis |
Multivariable analysis† |
||||||
OR (95% CI) | p value | OR (95% CI) | p value | ||||
stx subtype | |||||||
stx negative | 12 (16.7) | 65 (83.3) | Reference | Reference | |||
stx2c | 7 (22.6) | 29 (77.4) | 1.31 (0.47–3.7) | 0.61 | 1.01 (0.35–2.94) | 0.978 | |
stx2a |
69 (54.3) |
69 (45.7) |
5.42 (2.69–10.91) |
<0.001 |
4.61 (2.24–9.48) |
<0.001 |
|
Age | |||||||
Child, <16 y | 22 (20.0) | 88 (80.0) | 0.28 (0.16–0.50) | <0.001 | 0.31 (0.17–0.58) | <0.001 | |
Adult, >16 y |
66 (46.8) |
75 (53.2) |
Reference |
Reference |
|||
Sex | |||||||
F | 55 (40.4) | 81 (59.6) | Reference | Reference | |||
M | 33 (28.7) | 82 (71.3) | 0.59 (0.35–1.01) | 0.053 | 0.81 (0.45–1.47) | 0.494 |
*OR, odds ratio; SNP, single-nucleotide polymorphism.
†Adjusted for each exposure variable (stx subtype, sex, age).
1These first authors contributed equally to this article.
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