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Volume 24, Number 2—February 2018
Research

Use of Pristinamycin for Macrolide-Resistant Mycoplasma genitalium Infection

Tim R.H. ReadComments to Author , Jørgen S. Jensen, Christopher K. Fairley, Mieken Grant, Jennifer A. Danielewski, Jenny Su, Gerald L. Murray, Eric P.F. Chow, Karen Worthington, Suzanne M. Garland, Sepehr N. Tabrizi, and Catriona S. Bradshaw
Author affiliations: Melbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia (T.R.H. Read, C.K. Fairley, M. Grant, E.P.F. Chow, K. Worthington, C.S. Bradshaw); Monash University, Melbourne, Victoria, Australia (T.R.H. Read, C.K. Fairley, G.L. Murray, E.P.F. Chow, C.S. Bradshaw); Statens Serum Institut, Copenhagen, Denmark (J.S. Jensen); Murdoch Children’s Research Institute, Parkville, Victoria, Australia (J.A. Danielewski, J. Su, G.L. Murray, S.M. Garland, S.N. Tabrizi); Royal Women’s Hospital, Parkville (J.A. Danielewski, J. Su, G.L. Murray, S.M. Garland, S.N. Tabrizi); University of Melbourne, Parkville (S.M. Garland, S.N. Tabrizi, C.S. Bradshaw)

Main Article

Figure 2

Mycoplasma genitalium bacterial loads (log10) and treatment outcomes, Melbourne Sexual Health Centre, Melbourne, Victoria, Australia, 2012–2016. A) M. genitalium load compared in urine (n = 67), rectal swab (n = 26), and cervical swab (n = 3) samples. For urine vs. rectal samples, p = 0.56; for urine vs. cervical samples, p = 0.70. B) Comparison of pretreatment M. genitalium loads in infections not cured (n = 26) and cured (n = 71) by pristinamycin. p<0.01. C) Comparison of M. genitalium load

Figure 2. Mycoplasma genitalium bacterial loads (log10) and treatment outcomes, Melbourne Sexual Health Centre, Melbourne, Victoria, Australia, 2012–2016. A) M. genitalium load compared in urine (n = 67), rectal swab (n = 26), and cervical swab (n = 3) samples. For urine vs. rectal samples, p = 0.56; for urine vs. cervical samples, p = 0.70. B) Comparison of pretreatment M. genitalium loads in infections not cured (n = 26) and cured (n = 71) by pristinamycin. p<0.01. C) Comparison of M. genitalium loads in pretreatment and posttreatment samples from cases in which pristinamycin failed (n = 26). p<0.001..Box plots indicate 25th percentile (bottom of box), 75th percentile (top of box), median (horizontal line within box), and range (whiskers). Dots represent outlying individual observations.Dots under the error bars indicate individual outliers.

Main Article

Page created: January 17, 2018
Page updated: January 17, 2018
Page reviewed: January 17, 2018
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