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Volume 24, Number 2—February 2018
Synopsis

Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012–2015

Ana Catarina Pratas, Pablo Goldschmidt, David Lebeaux, Claire Aguilar, Natalia Ermak, Jonathan Benesty, Caroline Charlier, Edgar Benveniste, Lilia Merabet, Neila Sedira, Emilie Hope-Rapp, Christine Chaumeil, Bahram Bodaghi, Emmanuel Héron, José-Alain Sahel, Olivier Lortholary, and Marie-Hélène ErreraComments to Author 
Author affiliations: Quinze-Vingts National Eye Hospital, Paris, France (A.C. Pratas, P. Goldschmidt, N. Ermak, J. Benesty, E. Benveniste, L. Merabet, N. Sedira, C. Chaumeil, B. Bodaghi, E. Héron, J.-A. Sahel, M.-H. Errera); DHU Sight Restore, Paris (A.C. Pratas, P. Goldschmidt, N. Ermak, J. Benesty, E. Benveniste, L. Merabet, N. Sedira, C. Chaumeil, B. Bodaghi, E. Héron, J.-A. Sahel, M.-H. Errera); Sorbonne Universités, Université Pierre and Marie Curie, Université Paris, Paris (A.C. Pratas, P. Goldschmidt, N. Ermak, J. Benesty, E. Benveniste, L. Merabet, N. Sedira, C. Chaumeil, B. Bodaghi, E. Héron, J.-A. Sahel, M.-H. Errera); Université Paris Descartes, Sorbonne Paris Cité, Assistance Publique–Hôpitaux de Paris, Necker-Enfants Malades Hospital, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Paris (D. Lebeaux, C. Aguilar, C. Charlier, O. Lortholary); Imagine Institute, Paris (D. Lebeaux, C. Aguilar, C. Charlier, O. Lortholary); Centre Hospitalier Sainte-Musse, Toulon, France (E. Hope-Rapp); Pitié-Salpêtrière Hospital, Paris (B. Bodaghi)

Main Article

Table 2

Comparison of HIV-negative and HIV-positive patients with ocular syphilis seen at a uveitis clinic, by epidemiologic characteristics, clinical presentations, and outcomes, Paris, France, 2012–2015*

HIV status HIV-negative patients, 
n = 15 patients, 22 eyes HIV-positive patients, n = 6 patients, 7 eyes p value
Median age (range), y
 48 (32–72)
 38.5 (22–61)
 0.28
Median duration from onset of uveitis to presentation (range), d
 7 (1–90)
 30 (1–120)
 0.98
Uveitis type, no. (% [of 29 eyes])
Placoid chorioretinitis 15 (51) 2 (7)
Retinitis 2 (7) 2 (7)
Optic neuritis 3 (10.5) 1 (3.5)
Anterior uveitis (plus iris gumma) 0 1 (3.5)
Neuroretinitis 1 (3.5) 0
Intermediate uveitis 1 (3.5) 0
Retinal vasculitis
 1 (3.5)
 0
Bilateral disease, no. (%) 7 (46) 1 (16.5)
Neurosyphilis, no. (%)
 4 (26)
 6 (50)
Mean initial visual acuity (range), logMAR score 0.9 (0–2.3) 1 (0–2) 0.61
BCVA (range) 2 weeks after starting treatment, logMAR score 0.5 (0–2.3) 1.2 (0.4–2) 0.0030
BCVA (range) at final follow-up, logMAR score 0.09 (0–0.5) 0.7 (0–2.3) 0.0139

*BCVA, best-corrected visual acuity; logMAR, logarithm of the minimum angle of resolution.

Main Article

Page created: January 17, 2018
Page updated: January 17, 2018
Page reviewed: January 17, 2018
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