Volume 24, Number 4—April 2018
Dispatch
Novel Highly Pathogenic Avian Influenza A(H5N6) Virus in the Netherlands, December 2017
Figure 2

Figure 2. Schematic representation of the HPAI H5N6 reassortant virus detected in the Netherlands. Two variants of HPAI H5N8 were detected in 2016; they have different PA gene segments, called PA I and PA II. The novel virus evolved from H5N8 viruses having a PA II gene segment, but obtained both novel NA and PB2 gene segments. The H5N6 viruses detected in Greece, Japan, and Taiwan have evolved from H5N8 viruses that have a PA I gene segment and have an N6 segment similar to the virus detected in the Netherlands. HPAI, highly pathogenic avian influenza; PB, polymerase basic; PA, polymerase acidic; HA, hemagglutinin; NP, nucleoprotein; NA, neuraminidase; MP, matrix protein; NS, nonstructural protein.