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Volume 24, Number 5—May 2018
Dispatch

Second Human Pegivirus in Hepatitis C Virus–Infected and Hepatitis C Virus/HIV-1–Co-infected Persons Who Inject Drugs, China

Haiying Wang1, Zhengwei Wan1, Qiang Sun1, Nalin Zhu, Tianyi Li, Xuqi Ren, Xiaoping An, Shuyun Deng, Yue Wu, Xiufen Li, Lin Li, Jingyun Li, Yigang Tong, and Shixing TangComments to Author 
Author affiliations: Southern Medical University, Guangzhou, China (H. Wang, Z. Wan, N. Zhu, Y. Wu, X. Li, S. Tang); Guangdong Provincial Key Laboratory of Tropical Disease Research, Guangzhou (H. Wang, Z. Wan, N. Zhu, Y. Wu, X. Li, S. Tang); Beijing Institute of Microbiology and Epidemiology, Beijing, China (Q. Sun, T. Li, X. An, L. Li, J. Li, Y. Tong); Guangdong Provincial Dermatology Hospital, Guangzhou (X. Ren); Nanfang Hospital, Guangzhou (S. Deng)

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Figure 2

Phylogenetic analysis of second human pegivirus (HPgV-2) isolates identified in our study (China) and abroad (UK and US). Phylogenetic trees of nucleotide sequences from complete sequences of HPgV-2 strains isolated in our study and elsewhere as well as hepatitis C virus and pegivirus strains from humans, simians, equids, bats, and rodents are included. The phylogenetic trees were constructed with the neighbor-joining tree method using MEGA6 software (http://www.megasoftware.net). Bootstrap anal

Figure 2. Phylogenetic analysis of second human pegivirus (HPgV-2) isolates identified in our study (China) and abroad (UK and US). Phylogenetic trees of nucleotide sequences from complete sequences of HPgV-2 strains isolated in our study and elsewhere as well as hepatitis C virus and pegivirus strains from humans, simians, equids, bats, and rodents are included. The phylogenetic trees were constructed with the neighbor-joining tree method using MEGA6 software (http://www.megasoftware.net). Bootstrap analysis with 1,000 replicates was performed to determine the robustness of branching; values are shown on branches. Scale bar indicates the estimated number of nucleotide substitutions per site. The near full-length genome sequences of HPgV-2 identified in this study have been submitted to GenBank under accession numbers KX528230 (HCV-121), KX528231 (IDU31), KY971606 (C346), MG457178 (SC-LS-01), MF770985 (HCV1241), and MF770986 (HCV1563). UK, United Kingdom; US, United States.

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1These authors contributed equally to this article.

Page created: April 17, 2018
Page updated: April 17, 2018
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