Volume 24, Number 7—July 2018
Research
Pneumococcal Meningitis in Adults after Introduction of PCV7 and PCV13, Israel, July 2009–June 20151
Table 2
Univariate analysis of clinical outcomes of meningitis versus nonmeningitis IPD patients, Israel, July 1, 2009–June 30, 2015*
Category | Pneumococcal meningitis, n = 221 | Nonmeningitis IPD, n = 2,124 | p value |
---|---|---|---|
Population with full data available | 213 | 2,123 | |
Overall no. deaths (case-fatality rate) | 33 (15.5) | 488 (23.0) | 0.0123 |
ICU admission | 115 (54.0) | 322 (15.2) | <0.0001 |
Ventilation required | 91 (42.7) | 405 (19.1) | <0.0001 |
Mean LOS, d† |
21.0 |
10.5 |
<0.0001 |
Percentile LOS, by days, % | |||
5 | 55 | 33 | |
10 | 38.5 | 21 | |
25 | 21 | 11 | |
50 | 15 | 6 | |
75 | 12 | 4 | |
90 |
10 |
2 |
|
Sepsis† | 10/180 (5.6) | 170/1,635 (10.4) | 0.0391 |
Discharged to long-term care facility† | 34/173 (19.7) | 104/1,490 (7.0) | <0.0001 |
*Values are no. (%) except as indicated. ICU, intensive care unit; IPD, invasive pneumococcal disease; LOS, length of stay.
†Outcome assessed only for those who were discharged (deaths were excluded).
1Some results from this study were presented at the 10th International Symposium on Pneumococci and Pneumococcal Diseases, June 26–30, 2016, Glasgow, Scotland.
2Additional members of the Israeli Adult Invasive Pneumococcal Disease Group are listed at the end of this article.