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Volume 24, Number 8—August 2018
Letter

Visceral Leishmaniasis in Traveler to Guyana Caused by Leishmania siamensis, London, UK

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To the Editor: In a case report of visceral leishmaniasis in a traveler returning from Guyana, Polley et al. identified Leishmania siamensis as the causative agent (1). However, we believe that the parasite responsible for this infection has been misidentified. Classification of parasites formerly identified as L. siamensis has recently been revisited (2) after description of a new species (L. martiniquensis) from the West Indies (3). All previously described L. siamensis strains, except 1, are now reported as L. martiniquensis. Their rDNA internal transcribed spacer 1 sequences are still deposited in GenBank under the name L. siamensis. The exception, reported from Thailand (GenBank accession no. JX195640), is the only known L. siamensis sample to date.

New analysis of Leishmania (Mundinia) sequences available in GenBank and of L. infantum showed no variability in L. martiniquensis, including the sequence (GenBank accession no. LT577674) reported by Polley et al. (1), and sequence divergence when compared with L. siamensis (32.4%), a Leishmania sp. from Ghana (32.3%) (4), L. enrietti (30.6%), and L. infantum (43.6%). L. martiniquensis has been reported worldwide (Florida, West Indies, central Europe, and Southeast Asia). However, L. siamensis has been reported only once (in Thailand).

If one considers possible quiescence of the parasite, and that the patient was from Guyana, migrated to the United Kingdom in 1967, and had a relevant travel history, including visits to France (2003), Ghana (2005), Caribbean Grenada (2012), and Guyana (2012 and 2013), the geographic origin of this infection is unknown. Moreover, the mode of transmission of L. martiniquensis is not yet clearly defined. In contrast to the report of Polley et al. (1), although the genus Sergentomyia could play a role in some foci of leishmaniasis, it has never been recorded in the Americas (5).

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Jérôme DepaquitComments to Author , Matthieu L. Kaltenbach, and Frédérick Gay

Author affiliations: Reims Champagne-Ardenne University, Rheims, France (J. Depaquit, M.L. Kaltenbach); Maison Blanche Hospital, Reims (J. Depaquit); Pitié-Salpêtrière Hospital, Paris, France (F. Gay); Sorbonne University, Paris (F. Gay)

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References

  1. Polley  SD, Watson  J, Chiodini  PL, Lockwood  DNJ. Visceral leishmaniasis in traveler to Guyana caused by Leishmania siamensis, London, UK. Emerg Infect Dis. 2018;24:1556. DOIPubMed
  2. Leelayoova  S, Siripattanapipong  S, Manomat  J, Piyaraj  P, Tan-Ariya  P, Bualert  L, et al. Leishmaniasis in Thailand: a review of causative agents and situations. Am J Trop Med Hyg. 2017;96:53442.PubMed
  3. Desbois  N, Pratlong  F, Quist  D, Dedet  JP. Leishmania (Leishmania) martiniquensis n. sp. (Kinetoplastida: Trypanosomatidae), description of the parasite responsible for cutaneous leishmaniasis in Martinique Island (French West Indies). Parasite. 2014;21:12. DOIPubMed
  4. Kwakye-Nuako  G, Mosore  MT, Duplessis  C, Bates  MD, Puplampu  N, Mensah-Attipoe  I, et al. First isolation of a new species of Leishmania responsible for human cutaneous leishmaniasis in Ghana and classification in the Leishmania enriettii complex. Int J Parasitol. 2015;45:67984. DOIPubMed
  5. Maia  C, Depaquit  J. Can Sergentomyia (Diptera, Psychodidae) play a role in the transmission of mammal-infecting Leishmania? Parasite. 2016;23:55. DOIPubMed

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Cite This Article

DOI: 10.3201/eid2408.172147

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Table of Contents – Volume 24, Number 8—August 2018

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Jérôme Depaquit, Faculte de Pharmacie, Parasitology, 51 Rue Cognacq-Jay, Rheims 51100, France

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Page created: July 18, 2018
Page updated: July 18, 2018
Page reviewed: July 18, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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