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Volume 24, Number 9—September 2018
Synopsis

Systematic Review and Meta-analysis of Postexposure Prophylaxis for Crimean-Congo Hemorrhagic Fever Virus among Healthcare Workers

Önder ErgönülComments to Author , Şiran Keske, Melis Gökçe Çeldir, İlayda Arjen Kara, Natalia Pshenichnaya, Gulzhan Abuova, Lucille Blumberg, and Mehmet Gönen
Author affiliations: Koç University, Istanbul, Turkey (Ö. Ergönül, M.G. Çeldir, İ.A. Kara, M. Gönen); American Hospital, Istanbul (Ş. Keske); Rostov State Medical University, Rostov-on-Don, Russia (N. Pshenichnaya); South-Kazakhstan State Pharmaceutical Academy, Shymkent, Kazakhstan (G. Abuova); National Institute for Communicable Diseases, Johannesburg, South Africa (L. Blumberg)

Main Article

Figure 2

Effectiveness of PEP and early treatment with ribavirin among healthcare workers exposed to patients infected with Crimean-Congo hemorrhagic fever virus, 1976–2017. A) Two-step meta-analysis of the effectiveness of PEP with ribavirin for preventing Crimean-Congo hemorrhagic fever virus infection. We could determine the effect estimates for only 4 individual studies, and we included 33 reports in the final pooled estimate. B) Two-step meta-analysis on the effectiveness of early ribavirin use for

Figure 2. Effectiveness of PEP and early treatment with ribavirin among healthcare workers exposed to patients infected with Crimean-Congo hemorrhagic fever virus, 1976–2017. A) Two-step meta-analysis of the effectiveness of PEP with ribavirin for preventing Crimean-Congo hemorrhagic fever virus infection. We could determine the effect estimates for only 4 individual studies, and we included 33 reports in the final pooled estimate. B) Two-step meta-analysis on the effectiveness of early ribavirin use for preventing death caused by Crimean-Congo hemorrhagic fever virus infection. We could determine the effect estimate for only 2 individual studies, and we included 33 reports in the final pooled estimate. OR, odds ratio; PEP, postexposure prophylaxis.

Main Article

Page created: August 14, 2018
Page updated: August 14, 2018
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