Seroepidemiology of Parechovirus A3 Neutralizing Antibodies, Australia, the Netherlands, and United States
Eveliina Karelehto, Lieke Brouwer, Kimberley Benschop, Jen Kok, Kerri Basile, Brendan McMullan, William Rawlinson, Julian Druce, Suellen Nicholson, Rangaraj Selvarangan, Christopher Harrison, Kamani Lankachandra, Hetty van Eijk, Gerrit Koen, Menno de Jong, Dasja Pajkrt, and Katja C. Wolthers
Author affiliations: Academic Medical Center, Amsterdam, the Netherlands (E. Karelehto, L. Brouwer, H. van Eijk, G. Koen, M. de Jong, D. Pajkrt, K.C. Wolthers); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (K. Benschop); Institute of Clinical Pathology and Medical Research, Westmead, New South Wales, Australia (J. Kok, K. Basile); Sydney Children's Hospital, Sydney, New South Wales, Australia (B. McMullan); Prince of Wales Hospital, Randwick, New South Wales, Australia (W. Rawlinson); Doherty Institute, Melbourne, Victoria, Australia (J. Druce, S. Nicholson); Children’s Mercy Hospital, Kansas City, Missouri, USA (R. Selvarangan, C. Harrison); Truman Medical Center, Kansas City (K. Lankachandra)
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Figure 1
Figure 1. Parechovirus A3 (PeV-A3 neutralizing antibody (nAb) seropositivity, Australia, the Netherlands, and United States. A) Overall nAb seropositivity with associated 95% CIs. Infants <1 year of age were excluded from the analysis. Seropositivity rates between the timepoints within each location were compared by using χ2 tests. B) Overall age-stratified PeV-A3 nAb seropositivity, including infants <1 year of age. Seropositivity was determined as a nAb titer of ≥1:8 or ≥1:32. C–F) Age-stratified PeV-A3 nAb seropositivity in C) the Netherlands; D) Missouri, USA; E) Victoria, Australia; and F) New South Wales, Australia. Complete data used in this figure can be found in the Appendix (http://wwwnc.cdc.gov/EID/article/25/1/18-0352-App1.pdf). AUS, Australia; NL, the Netherlands; NSW, New South Wales; VIC, Victoria.
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