Emergence of Influenza A(H7N4) Virus, Cambodia
Dhanasekaran Vijaykrishna, Yi-Mo Deng, Miguel L. Grau, Matthew Kay, Annika Suttie, Paul F. Horwood, Wantanee Kalpravidh, Filip Claes, Kristina Osbjer, Phillipe Dussart, Ian G. Barr, and Erik A. Karlsson
Author affiliations: Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia (D. Vijaykrishna, Y.-M. Deng, M. Kay, I.G. Barr); Monash University, Melbourne (D. Vijaykrishna, M.L. Grau); Institut Pasteur du Cambodge, Phnom Penh, Cambodia (A. Suttie, P.F. Horwood, P. Dussart, E.A. Karlsson); James Cook University, Townsville, Queensland, Australia (P.F. Horwood); Food and Agriculture Organization of the United Nations, Bangkok, Thailand (W. Kalpravidh, F. Claes); Food and Agriculture Organization of the United Nations, Phnom Penh, Cambodia (K. Osbjer)
Figure. Maximum-likelihood phylogeny of the evolutionary origins of influenza A(H7N4) virus in Cambodia and comparison with reference isolates. H7 hemagglutinin (A) and N4 neuraminidase (B) genes were inferred using a general time-reversible nucleotide substitution model with a gamma distribution of among-site rate variation in RAxML version 8 (https://cme.h-its.org/exelixis/web/software/raxml) and visualized using Figtree version 1.4 (http://tree.bio.ed.ac.uk/software/figtree/). Branch support values were generated using 1,000 bootstrap replicates. Green indicates A/Anhui 1/2013-like lineage viruses; red indicates viruses from Cambodia; blue indicates A/Jiangsu/2018-like viruses. Scale bars represent nucleotide substitutions per site.
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