Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 25, Number 12—December 2019
Research

High Prevalence of Macrolide-Resistant Bordetella pertussis and ptxP1 Genotype, Mainland China, 2014–2016

Lijun Li1, Jikui Deng1, Xiang Ma1, Kai Zhou1, Qinghong Meng, Lin Yuan, Wei Shi, Qing Wang, Yue Li, and Kaihu YaoComments to Author 
Author affiliations: Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, Beijing, China (L. Li, Q. Meng, L. Yuan, W. Shi, Q. Wang, Y. Li, K. Yao); Shenzhen Children’s Hospital, Shenzhen, China (J. Deng); Jinan Children’s Hospital, Shandong University, Shandong, China (X. Ma); Nanjing Children’s Hospital, Nanjing Medical University, Nanjing, China

Main Article

Table 3

Genotype profiles for 335 Bordetella pertussis isolates from mainland China, 2014–2016

Genotype profile*
 No. (%) isolates
Total
Region
Year
 Northern China
 Southern China
 Other†
2014
 2015
 2016
ptxA1/ptxC1/ptxP1/prn1/fim2–1/fim3A/tcfA2 5 (1.5) 0 3 (1.7) 2 (1.5) 2 (0.9) 3 (5.4) 0
ptxA1/ptxC2/ptxP1/prn1/fim2–1/fim3A/tcfA2 1 (0.3) 0 1 (0.6) 0 1 (0.5) 0 0
ptxA1/ptxC1/ptxP1/prn3/fim2–1fim3A/tcfA2 1 (0.3) 0 1 (0.6) 0 0 1 (1.8) 0
ptxA1/ptxC2/ptxP3/prn9/fim2–1/fim3A/tcfA2 1 (0.3) 0 0 1 (0.7) 0 1 (1.8) 0
ptxA1/ptxC2/ptxP3/prn2/fim2–1/fim3B/tcfA2 2 (0.6) 1 (3.7) 1 (0.6) 0 2 (0.9) 0 0
ptxA1/ptxC1/ptxP3/prn2/fim2–1/fim3A/tcfA2 5 (1.5) 1 (3.7) 3 (1.7) 1 (0.7) 5 (2.3) 0 0
ptxA1/ptxC2/ptxP3/prn2/fim2–1/fim3A/tcfA2 28 (8.4) 0 8 (4.7) 20 (14.7) 10 (4.7) 15 (26.8) 3 (4.5)
ptxA1/ptxC1/ptxP1/prn1/fim2–1/fim3A/tcfA2 292 (87.2) 25 (92.6) 155 (90.1) 112 (82.4) 193 (90.6) 36 (64.3) 63 (95.5)
Total 335 (100) 27 (100) 172 (100) 136 (100) 213 (100) 56 (100) 66 (100)

*Genotype of vaccine strain in China: ptxA2/ptxC1/ptxP1/prn1/fim2–1/fim3A/tcfA2.
†Northeastern, northwestern, eastern, and central southern China.

Main Article

1These authors contributed equally to this article.

Page created: November 18, 2019
Page updated: November 18, 2019
Page reviewed: November 18, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external