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Volume 25, Number 12—December 2019
Dispatch

Cat-to-Human Transmission of Mycobacterium bovis, United Kingdom

Catherine M. O’ConnorComments to Author , Muhammad Abid1, Amanda L. Walsh, Behrooz Behbod2, Tony Roberts, Linda V. Booth, H. Lucy Thomas, Noel H. Smith, Eleftheria Palkopoulou, James Dale, Javier Nunez-Garcia3, and Dilys Morgan
Author affiliations: Public Health England, London, UK (C.M. O’Connor, A.L. Walsh, H.L. Thomas, D. Morgan); Public Health England, Chilton, UK (M. Abid, B. Behbod); Animal and Plant Health Agency, Oxford, UK (T. Roberts); Public Health England, Fareham, UK (L.V. Booth); Animal and Plant Health Agency, Weybridge, UK (N.H. Smith, E. Palkopoulou, J. Dale, J. Nunez-Garcia)

Main Article

Figure

Whole-genome sequencing phylogenetic relationship of genotype 10:u isolates of Mycobacterium bovis from 1 human, 7 cats, 11 cattle, and 1 alpaca, and 10:a isolates from 3 cattle (maximum-likelihood tree of all single-nucleotide polymorphisms [SNPs]). Cat and human isolates are indicated by solid arrowheads. Heat-killed cultures were sequenced by using a MiSeq Sequencer (Illumina, https://www.illumina.com), and reads were mapped by using reference strain AF2122. The average coverage ranged from 2

Figure. Whole-genome sequencing phylogenetic relationship of genotype 10:u isolates of Mycobacterium bovis from 1 human, 7 cats, 11 cattle, and 1 alpaca, and 10:a isolates from 3 cattle (maximum-likelihood tree of all single-nucleotide polymorphisms [SNPs]). Cat and human isolates are indicated by solid arrowheads. Heat-killed cultures were sequenced by using a MiSeq Sequencer (Illumina, https://www.illumina.com), and reads were mapped by using reference strain AF2122. The average coverage ranged from 23.9-fold to 88.8-fold. The human and their household cat contact (cat 5) isolates were indistinguishable in their genome sequences. Scale bar indicates SNPs.

Main Article

1Current affiliation: United Arab Emirates University, Al Ain, United Arab Emirates.

2Current affiliations: Communicable Disease Surveillance Centre, Public Health Wales, Cardiff, Wales, UK, and Cardiff University, Cardiff.

3Current affiliation: Genomics Medicine Ireland, Dublin, Ireland.

Page created: November 18, 2019
Page updated: November 18, 2019
Page reviewed: November 18, 2019
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