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Volume 25, Number 2—February 2019
CME ACTIVITY - Research

Acute and Delayed Deaths after West Nile Virus Infection, Texas, USA, 2002–2012

David C.E. Philpott1, Melissa S. Nolan, Nicole Evert, Bonny Mayes, Dawn Hesalroad, Eric Fonken, and Kristy O. MurrayComments to Author 
Author affiliations: Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, USA (D.C.E. Philpott, M.S. Nolan, K.O. Murray); Texas Department of State Health Services, Austin, Texas, USA (N. Evert, B. Mayes, D. Hesalroad, E. Fonken)

Main Article

Table 3

SMRs for convalescent-phase deaths caused by WNND stratified by age at WNV infection symptom onset, Texas, USA, 2002–2012*

ICD-10 code Cause of death or disorder <60 years of age
>60 years of age
No. deaths observed No. deaths expected SMR (95% CI) No. deaths observed No. deaths expected SMR (95% CI)
Any All cause 52 26.26 1.98 (1.51–2.60) 158 159.76 0.99 (0.84–1.16)
A00-B99 Infectious 7 1.31 5.33 (2.54–11.17) 19 4.18 4.55 (2.90–7.13)
C00-D48 Neoplasms 8 7.24 1.11 (0.55–2.21) 25 36.73 0.68 (0.46–1.01)
E00-E90 Endocrine 1 1.29 0.78 (0.11–5.51) 10 6.686 1.46 (0.79–2.72)
F00-F99 Mental and behavioral 2 0.32 6.28 (1.57–25.12) 11 8.64 1.27 (0.70–2.30)
G00-G99 Nervous system 2 0.61 3.27 (0.82–13.07) 9 10.09 0.89 (0.46–1.71)
I00-I99 Circulatory system 14 6.94 2.02 (1.19–3.41) 50 56.50 0.88 (0.67–1.17)
J00-J99 Respiratory system 2 1.42 1.40 (0.35–5.62) 11 18.27 0.60 (0.33–1.09)
K00-K93 Digestive system 7 1.81 3.87 (1.85–8.12) 2 5.01 0.40 0.10–1.60)
N00-N99 Genitourinary system 6 0.51 11.72 (5.26–26.08) 7 4.89 1.43 (0.68–3.00)
N00-N19 Renal system 5 0.44 11.37 (4.73–27.31) 6 3.81 1.58 (0.71–3.51)
R00-R99 Other 0 0.42 0 (NA) 5 2.11 2.36 (0.98–5.68)
W00-Y98 External forces 3 2.83 1.06 (0.34–3.29) 7 4.01 1.75 (0.83–3.66)

*Deaths and SMR were calculated only for cases with information about age available and in which death occurred >90 d after symptom onset. SMR was 1 when there was no increased risk. Bold indicates statistical significance. ICD-10, International Classification of Diseases, 10th Revision; NA, not applicable; SMR, standardized mortality ratio adjusted for current age, sex, and calendar year; WNND, West Nile neuroinvasive disease; WNV, West Nile virus.

Main Article

1Current affiliation: Johns Hopkins Children’s Center, Baltimore, Maryland, USA.

Page created: January 17, 2019
Page updated: January 17, 2019
Page reviewed: January 17, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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