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Volume 25, Number 2—February 2019
Research

Zika Virus IgM Detection and Neutralizing Antibody Profiles 12–19 Months after Illness Onset

Isabel GriffinComments to Author , Stacey W. Martin, Marc Fischer, Trudy V. Chambers, Olga Kosoy, Alyssa Falise, Olga Ponomareva, Leah D. Gillis, Carina Blackmore, and Reynald Jean
Author affiliations: Florida Department of Health in Miami–Dade County, Miami, Florida, USA (I. Griffin, A. Falise, O. Ponomareva, R. Jean); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (S.W. Martin, M. Fischer, T.V. Chambers, O. Kosoy); Bureau of Public Health Laboratories, Miami (L.D. Gillis); Florida Department of Health, Tallahassee, Florida, USA (C. Blackmore)

Main Article

Table 2

Demographic and clinical characteristics of enrolled participants in Miami–Dade County, Florida, USA, with PCR-confirmed Zika virus disease by Zika virus IgM antibody result 12–19 months after illness onset (n = 62)

Characteristic Zika virus IgM results 12–19 mo after symptom onset, no. (%)*
 p value†
Positive Equivocal Negative
Age group, y 0.58
1–18, n = 2 2 (100) 0 0
19–64, n = 54 38 (71) 12 (22) 4 (7)
>65, n = 6
 5 (83)
 0
 1 (17)
Sex 0.30
M, n = 32 25 (78) 6 (19) 1 (3)
F, n = 30
 20 (67)
 6 (20)
 4 (13)
Race/ethnicity 0.18
Non-Hispanic white, n = 12 11 (92) 1 (8) 0
Non-Hispanic African American, n = 4 1 (25) 2 (50) 1 (25)
Hispanic, n = 42 29 (69) 9 (21) 4 (10)
Unknown, n = 4
 4 (100)
 0
 0
Main symptoms of Zika virus‡ 0.28
1 of 4, n = 2 1 (50) 1 (50) 0
2 of 4, n = 15 8 (54) 5 (33) 2 (13)
3 of 4, n = 32 25 (78) 4 (13) 3 (9)
4 of 4, n = 13
 11 (85)
 2 (15)
 0
Origin of infection 0.52
Florida, n = 34 24 (70) 6 (18) 4 (12)
Outside Florida, n = 28 21 (75) 6 (21) 1 (4)

*All percentages are row percentages.
†A p-value <0.05 was considered statistically significant.
‡Main symptoms were defined as fever, maculopapular rash, arthralgia, and conjunctivitis.

Main Article

Page created: January 16, 2019
Page updated: January 16, 2019
Page reviewed: January 16, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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