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Volume 25, Number 3—March 2019

Acute Flaccid Myelitis Associated with Enterovirus D68 in Children, Argentina, 2016

Carolina M. CarballoComments to Author , Marcela García Erro, Nora Sordelli, Gabriel Vazquez, Alicia S. Mistchenko, Claudia Cejas, Manlio Rodriguez, Daniel M. Cisterna, Maria Cecilia Freire, Maria M. Contrini, and Eduardo L. Lopez
Author affiliations: Hospital de Niños “Ricardo Gutiérrez,” Buenos Aires, Argentina (C.M. Carballo, M. García Erro, N. Sordelli, A.S. Mistchenko, M. Rodriguez, M.M. Contrini, E.L. Lopez); Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI), Buenos Aires (G. Vazquez, C. Cejas); Administración Nacional de Laboratorios e Institutos de Salud (ANLIS) “Dr. Carlos G. Malbrán,” Buenos Aires (D.M. Cisterna, M.C. Freire)

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Table 1

Demographics, neurologic symptoms, and clinical outcomes for patients with acute flaccid myelitis, Argentina, 2016

Feature Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6
Age, mo/sex 34/M 15/F 35/M 60/F 12/F 60/F
History of asthma
Preceding illness
Fever No Yes Yes Yes Yes No
URTI Yes Yes Yes Yes Yes Yes
Gastrointestinal symptoms
Neurologic symptoms
Limb, back, or neck pain Yes Yes Yes Yes Yes Yes
Arm weakness Yes (bilateral) Yes (right) No Yes (left) Yes (bilateral) Yes (bilateral)
Leg weakness Yes (bilateral) Yes
asymmetric, bilateral) Yes (left progressive to bilateral, asymmetric) Yes (progressive, asymmetric, bilateral) Yes (bilateral) Yes (bilateral)
Neck weakness Yes Yes No Yes Yes Yes
Facial weakness No No No Yes No Yes
Sensitivity involvement No No No No No No
Mental status involvement No No No No No No
Other neurologic deficits
Bulbar weakness
Left VII cranial nerve palsy
Bilateral VII cranial nerve palsy; bulbar weakness; tetraparesis
Severity of disease
ICU care; mechanical ventilation; tracheostomy; feeding support
ICU care; noninvasive positive pressure ventilation; feeding support
Progressive asymmetric 4- limb weakness
ICU care; mechanical ventilation; tracheostomy;
feeding support
Outcome/sequelae Persistent weakness; feet atrophy; equinus left foot; chronic noninvasive ventilation support Partial recovery of weakness
Atrophy of left foot Recovery of right leg weakness;
equinus left foot Persistent leg left paralysis; 2 cm atrophy in left quadriceps Persistent left arm paralysis and left leg weakness Persistent leg paralysis and arm weakness; noninvasive ventilation support
Duration of hospitalization 6 mo 14 d 10 d 46 d 8 d 4 mo

*ICU, intensive care unit; URTI, upper respiratory tract infection.

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Page created: February 19, 2019
Page updated: February 19, 2019
Page reviewed: February 19, 2019
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