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Volume 25, Number 3—March 2019
Dispatch

Acute Flaccid Myelitis Associated with Enterovirus D68 in Children, Argentina, 2016

Carolina M. CarballoComments to Author , Marcela García Erro, Nora Sordelli, Gabriel Vazquez, Alicia S. Mistchenko, Claudia Cejas, Manlio Rodriguez, Daniel M. Cisterna, Maria Cecilia Freire, Maria M. Contrini, and Eduardo L. Lopez
Author affiliations: Hospital de Niños “Ricardo Gutiérrez,” Buenos Aires, Argentina (C.M. Carballo, M. García Erro, N. Sordelli, A.S. Mistchenko, M. Rodriguez, M.M. Contrini, E.L. Lopez); Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI), Buenos Aires (G. Vazquez, C. Cejas); Administración Nacional de Laboratorios e Institutos de Salud (ANLIS) “Dr. Carlos G. Malbrán,” Buenos Aires (D.M. Cisterna, M.C. Freire)

Main Article

Table 1

Demographics, neurologic symptoms, and clinical outcomes for patients with acute flaccid myelitis, Argentina, 2016

Feature Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6
Age, mo/sex 34/M 15/F 35/M 60/F 12/F 60/F
History of asthma
No
No
No
Yes
Yes
Yes
Preceding illness
Fever No Yes Yes Yes Yes No
URTI Yes Yes Yes Yes Yes Yes
Gastrointestinal symptoms
No
No
Yes
No
No
No
Neurologic symptoms
Limb, back, or neck pain Yes Yes Yes Yes Yes Yes
Arm weakness Yes (bilateral) Yes (right) No Yes (left) Yes (bilateral) Yes (bilateral)
Leg weakness Yes (bilateral) Yes
(progressive,
asymmetric, bilateral) Yes (left progressive to bilateral, asymmetric) Yes (progressive, asymmetric, bilateral) Yes (bilateral) Yes (bilateral)
Neck weakness Yes Yes No Yes Yes Yes
Facial weakness No No No Yes No Yes
Sensitivity involvement No No No No No No
Mental status involvement No No No No No No
Other neurologic deficits
Bulbar weakness
No
No
Left VII cranial nerve palsy
No
Bilateral VII cranial nerve palsy; bulbar weakness; tetraparesis
Severity of disease
ICU care; mechanical ventilation; tracheostomy; feeding support
Weakness
Weakness
ICU care; noninvasive positive pressure ventilation; feeding support
Progressive asymmetric 4- limb weakness
ICU care; mechanical ventilation; tracheostomy;
feeding support
Outcome/sequelae Persistent weakness; feet atrophy; equinus left foot; chronic noninvasive ventilation support Partial recovery of weakness
Atrophy of left foot Recovery of right leg weakness;
equinus left foot Persistent leg left paralysis; 2 cm atrophy in left quadriceps Persistent left arm paralysis and left leg weakness Persistent leg paralysis and arm weakness; noninvasive ventilation support
Duration of hospitalization 6 mo 14 d 10 d 46 d 8 d 4 mo

*ICU, intensive care unit; URTI, upper respiratory tract infection.

Main Article

Page created: February 19, 2019
Page updated: February 19, 2019
Page reviewed: February 19, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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