Volume 25, Number 3—March 2019
Synopsis
Epidemiology of Extrapulmonary Tuberculosis among Inpatients, China, 2008–2017
Yu Pang1, Jun An1, Wei Shu1, Fengmin Huo, Naihui Chu, Mengqiu Gao, Shibing Qin, Hairong Huang, Xiaoyou Chen, and Shaofa Xu
Table 3
Multivariate analysis of risk factors for 7 types of extrapulmonary TB compared with pulmonary TB, China, 2008–2017*
| Patient characteristic | Odds ratio (95% CI) |
||||||
|---|---|---|---|---|---|---|---|
| Skeletal, n = 2,643 | Pleural, n = 1,673 | Meningeal, n = 440 | Disseminated, n = 427 | Lymphatic, n = 333 | Genitourinary, n = 44 | Others, n = 873 | |
| Sex | |||||||
| M | Referent | Referent | Referent | Referent | Referent | Referent | Referent |
| F |
1.64
(1.49–1.81) |
0.76
(0.67–0.86) |
1.15
(0.93–1.43) |
1.68
(1.36–2.08) |
4.11
(3.17–5.34) |
5.74
(2.77–11.90) |
1.27
(1.09–1.48) |
| Age group, y | |||||||
| <25 | 1.14 (0.97–1.33) | 2.26 (1.88–2.70) | 3.24 (2.17–4.86) | 2.32 (1.65–3.26) | 3.54 (2.14–5.85) | 2.26 (0.46–11.70) | 1.92 (1.45–2.54) |
| 25–44 | 1.08 (0.93–1.25) | 1.86 (1.57–2.20) | 3.06 (2.09–4.49) | 1.38 (0.98–1.93) | 4.93 (3.09–7.87) | 3.48 (0.76–15.93) | 2.06 (1.59–2.66) |
| 45–64 | 1.33 (1.16–1.52) | 1.01 (0.85–1.21) | 1.65 (1.11–2.46) | 0.78 (0.54–1.12) | 2.09 (1.26–3.46) | 5.85 (1.33–25.78) | 1.83 (1.42–2.36) |
| ≥65 |
Referent |
Referent |
Referent |
Referent |
Referent |
Referent |
Referent |
| Residence | |||||||
| Rural | Referent | Referent | Referent | Referent | Referent | Referent | Referent |
| Urban |
0.63
(0.56–0.70) |
0.94
(0.82–1.07) |
0.68
(0.54–0.86) |
0.69
(0.54–0.87) |
1.92
(1.35–2.73) |
0.91
(0.45–1.85) |
0.83
(0.70–0.98) |
| Treatment history | |||||||
| New case | Referent | Referent | Referent | Referent | Referent | Referent | Referent |
| Retreated case |
0.06
(0.04–0.09) |
0.14
(0.10–0.20) |
0.24
(0.14–0.40) |
0.31
(0.19–0.49) |
0.36
(0.22–0.58) |
0.29
(0.07–1.20) |
0.95
(0.77–1.17) |
| Diabetes | |||||||
| No | Referent | Referent | Referent | Referent | Referent | Referent | Referent |
| Yes |
0.84
(0.61–1.16) |
0.29
(0.16–0.54) |
0.25
(0.06–1.03) |
0.62
(0.23–1.68) |
0.18
(0.02–1.30) |
– |
0.34
(0.15–0.77) |
| Culture determination | |||||||
| Negative | Referent | Referent | Referent | Referent | Referent | Referent | Referent |
| Positive |
0.13
(0.12–0.15) |
0.15
(0.13–0.18) |
0.05
(0.03–0.08) |
0.36
(0.29–0.47) |
0.02
(0.01–0.06) |
0.14
(0.05–0.38) |
0.31
(0.26–0.37) |
| *The pulmonary TB group was set as a reference for each comparison in multivariate analysis. Odds ratios were adjusted for all variables used in this model. Bold indicates significance. TB, tuberculosis. | |||||||
1These authors contributed equally to this article.
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