Volume 25, Number 3—March 2019
CME ACTIVITY - Synopsis
Bacillus Calmette-Guérin Cases Reported to the National Tuberculosis Surveillance System, United States, 2004–2015
Zimy Wansaula
, Jonathan M. Wortham , Godwin Mindra, Maryam B. Haddad, Jorge L. Salinas, David Ashkin, Sapna B. Morris, Gail B. Grant, Smita Ghosh, and Adam J. Langer
, Jonathan M. Wortham , Godwin Mindra, Maryam B. Haddad, Jorge L. Salinas, David Ashkin, Sapna B. Morris, Gail B. Grant, Smita Ghosh, and Adam J. Langer
Table 1
Characteristics of BCG-related cases and TB cases reported, National Tuberculosis Surveillance System — United States, 2004–2015*
| Characteristic | BCG cases, no. (%) | TB cases, no. (%) |
|---|---|---|
| Total cases reported, no. (%) | 118 (100) | 91,065 (100) |
| Median age (interquartile range), y |
75 (66–81) |
47 (31–62) |
| Age group, y | ||
| 0–4 | 6 (5) | 954 (1) |
| 5–14 | 0 | 856 (0.9) |
| 15–24 | 2 (2) | 10,398 (11) |
| 25–44 | 3 (3) | 30,236 (33) |
| 45–64 | 16 (14) | 28,327 (31) |
| >65 |
91 (77) |
20,289 (22) |
| Sex | ||
| M | 110 (93) | 56,800 (62) |
| F |
8 (7) |
34,265 (38) |
| White, non-Hispanic | 95 (81) | 14,330 (16) |
| US-born |
101 (86) |
35,215 (38.7) |
| Pulmonary disease only | 15 (13) | 67,033 (74) |
| Extrapulmonary disease only | 98 (83) | 14,659 (16) |
| Both pulmonary and extrapulmonary disease |
5 (4) |
9,336 (10) |
| Extrapulmonary sites of disease† | ||
| Bones and joints | 37 (36) | 2,953 (12) |
| Genitourinary | 30 (29) | 1435 (6) |
| Lymphatic system | 4 (4) | 9,088 (38) |
| Peritoneal | 4 (4) | 1,473 (6) |
| Pleural | 3 (3) | 5,428 (3) |
| Meningeal | 0 | 1,203 (5) |
| Other extrapulmonary sites‡ |
30 (29) |
3,453 (14) |
| History of long-term care facility residency | 11 (9) | 1,988 (2) |
| Diabetes§ | 15 (21) | 7,864 (17) |
*BCG, Bacillus Calmette-Guérin; TB, tuberculosis.
†Denominators for percentages are based on the preceding 2 rows of all cases with any extrapulmonary involvement (i.e., with or without pulmonary involvement).
‡Include blood, urinary bladder, subcutaneous tissues, and bone marrow.
§Diabetes comorbidity data only available starting in 2009; therefore, percentages are based on different denominators (45,786 TB cases and 72 BCG cases).
Page created: February 19, 2019
Page updated: February 19, 2019
Page reviewed: February 19, 2019
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