Volume 25, Number 3—March 2019
Research
Increased Risk for Invasive Group A Streptococcus Disease for Household Contacts of Scarlet Fever Cases, England, 2011–2016
Vicky Watts
, Sooria Balasegaram, Colin S. Brown, Suzanna Mathew, Rachel Mearkle, Derren Ready, Vanessa Saliba, and Theresa Lamagni
, Sooria Balasegaram, Colin S. Brown, Suzanna Mathew, Rachel Mearkle, Derren Ready, Vanessa Saliba, and Theresa Lamagni
Table 2
Risk for iGAS infection among household contacts of scarlet fever case-patients <10 years of age by year compared with background iGAS incidence, England, 2011–2016*
| Year | No. scarlet fever cases | Estimated no. contacts | No. iGAS cases in contacts† | Attack rate/100,000 person-years (95% CI) | Background iGAS incidence/100,000 person-years | Rate ratio (95% CI) |
|---|---|---|---|---|---|---|
| 2011 |
3,128 |
8,929 |
0 |
0.0 (0.0–251.5) |
2.29 |
NA |
| 2012 |
4,632 |
13,073 |
0 |
0.0 (0.0–171.8) |
2.35 |
NA |
| 2013 |
5,204 |
14,778 |
0 |
0.0 (0.0–152.0) |
2.99 |
NA |
| 2014 |
16,394 |
47,015 |
3 |
38.8 (8.0–113.5) |
2.29 |
16.9 (5.5–52.6) |
| 2015 |
18,022 |
51,454 |
3 |
35.5 (7.3–103.7) |
3.48 |
10.2 (3.3–31.7) |
| 2016 |
18,811 |
54,435 |
5 |
55.9 (18.2–130.5) |
3.91 |
14.3 (5.9–34.7) |
| Total | 66,191 | 189,684 | 11 | 35.3 (17.6–63.2) | 2.89 | 12.2 (6.7–22.1) |
*iGAS, invasive group A Streptococcus infection; NA, not applicable.
†During the 60 days after onset of scarlet fever in the household.
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Page updated: February 19, 2019
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