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Volume 25, Number 5—May 2019

CME ACTIVITY - Research

Age-Dependent Increase in Incidence of Staphylococcus aureus Bacteremia, Denmark, 2008–2015

Louise Thorlacius-UssingComments to Author , Haakon Sandholdt, Anders Rhod Larsen, Andreas Petersen, and Thomas Benfield
Author affiliations: Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark (L. Thorlacius-Ussing, H. Sandholdt, T. Benfield); Statens Serum Institut, Copenhagen (A. Larsen, A. Petersen)

Main Article

Table 3

CFR and associated risk of Staphylococcus aureus bacteremia, Denmark, 2008–2015*

Characteristic 30-d CFR (95% CI) Multivariate OR (CI 95%) p value
Sex
M 21.88 (20.79–23.01) Referent NA
F
26.92 (25.36–28.54)
1.20 (1.08–1.33)
<0.001
Age, y
<1 6.74 (4.06–10.52) 4.68 (1.05–20.85) 0.043
1–9 2.55 (0.69–6.52) Referent NA
10–19 1.92 (0.52–4.92) 1.71 (0.31–9.50) 0.538
20–29 2.94 (1.08–6.40) 2.22 (0.44–11.20) 0.333
30–39 2.13 (0.92–4.21) 1.36 (0.28–6.64) 0.705
40–49 9.47 (7.45–11.87) 6.37 (1.54–26.34) 0.011
50–59 16.44 (14.33–18.77) 10.79 (2.64–44.06) <0.001
60–69 19.79 (18.08–21.62) 13.00 (3.19–52.89) <0.001
70–79 27.80 (25.80–29.92) 19.69 (4.85–79.94) <0.001
80–89 38.10 (35.51–40.82) 32.26 (7.94–131.03) <0.001
>90
51.93 (46.05–58.36)
58.48 (14.26–239.82
<0.001
CCI score
0 14.20 (12.79–15.72) Referent NA
1–2 23.90 (22.44–25.43) 1.32 (1.14–1.55) <0.001
>3
29.46 (27.86–31.13)
1.67 (1.43–1.94)
<0.001
Hospital contact within 90 d
No 22.21 (20.34–24.23) Referent NA
Yes
23.98 (22.82–25.18)
1.10 (0.97–1.24)
0.130
Period, per-year increment NA 0.99 (0.97–1.01) 0.044

*CCI, Charlson Comorbidity Index; CFR, case-fatality rate; NA, not applicable; OR, odds ratio.

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