Volume 25, Number 5—May 2019
CME ACTIVITY - Research
Age-Dependent Increase in Incidence of Staphylococcus aureus Bacteremia, Denmark, 2008–2015
Louise Thorlacius-Ussing
, Haakon Sandholdt, Anders Rhod Larsen, Andreas Petersen, and Thomas Benfield
, Haakon Sandholdt, Anders Rhod Larsen, Andreas Petersen, and Thomas Benfield
Table 3
CFR and associated risk of Staphylococcus aureus bacteremia, Denmark, 2008–2015*
| Characteristic | 30-d CFR (95% CI) | Multivariate OR (CI 95%) | p value |
|---|---|---|---|
| Sex | |||
| M | 21.88 (20.79–23.01) | Referent | NA |
| F |
26.92 (25.36–28.54) |
1.20 (1.08–1.33) |
<0.001 |
| Age, y | |||
| <1 | 6.74 (4.06–10.52) | 4.68 (1.05–20.85) | 0.043 |
| 1–9 | 2.55 (0.69–6.52) | Referent | NA |
| 10–19 | 1.92 (0.52–4.92) | 1.71 (0.31–9.50) | 0.538 |
| 20–29 | 2.94 (1.08–6.40) | 2.22 (0.44–11.20) | 0.333 |
| 30–39 | 2.13 (0.92–4.21) | 1.36 (0.28–6.64) | 0.705 |
| 40–49 | 9.47 (7.45–11.87) | 6.37 (1.54–26.34) | 0.011 |
| 50–59 | 16.44 (14.33–18.77) | 10.79 (2.64–44.06) | <0.001 |
| 60–69 | 19.79 (18.08–21.62) | 13.00 (3.19–52.89) | <0.001 |
| 70–79 | 27.80 (25.80–29.92) | 19.69 (4.85–79.94) | <0.001 |
| 80–89 | 38.10 (35.51–40.82) | 32.26 (7.94–131.03) | <0.001 |
| >90 |
51.93 (46.05–58.36) |
58.48 (14.26–239.82 |
<0.001 |
| CCI score | |||
| 0 | 14.20 (12.79–15.72) | Referent | NA |
| 1–2 | 23.90 (22.44–25.43) | 1.32 (1.14–1.55) | <0.001 |
| >3 |
29.46 (27.86–31.13) |
1.67 (1.43–1.94) |
<0.001 |
| Hospital contact within 90 d | |||
| No | 22.21 (20.34–24.23) | Referent | NA |
| Yes |
23.98 (22.82–25.18) |
1.10 (0.97–1.24) |
0.130 |
| Period, per-year increment | NA | 0.99 (0.97–1.01) | 0.044 |
*CCI, Charlson Comorbidity Index; CFR, case-fatality rate; NA, not applicable; OR, odds ratio.
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Page updated: April 12, 2019
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