Volume 25, Number 8—August 2019
CME ACTIVITY - Synopsis
Zika Virus Infection in Pregnant Women, Yucatan, Mexico
Yamila Romer
, Nina Valadez-Gonzalez, Silvina Contreras-Capetillo, Pablo Manrique-Saide, Gonzalo Vazquez-Prokopec, and Norma Pavia-Ruz
, Nina Valadez-Gonzalez, Silvina Contreras-Capetillo, Pablo Manrique-Saide, Gonzalo Vazquez-Prokopec, and Norma Pavia-Ruz
Table 5
Outcomes of pregnancy and for newborn children born to Zika virus–infected and –noninfected mothers, Yucatan, Mexico*
| Outcome | Zika virus–positive mothers, n = 31 | Zika virus–negative mothers, n = 69 | Total, n = 100 | p value† | Odds ratio |
|---|---|---|---|---|---|
| Pregnancy‡ | |||||
| Live births | NA | NA | NA | NA | NA |
| Term | 30 (97) | 67 (97) | NA | 0.90 | 0.89 |
| Preterm |
1 (3) |
2 (3) |
NA |
0.90 |
1.10 |
| Fetal loss, trimester | |||||
| First | 0 | 2 (2) | 2 (2) | NA | NA |
| Second | 0 | 0 | 0 | NA | NA |
| Third |
0 |
1 (1) |
1 (1) |
NA |
NA |
| Newborn | |||||
| APGAR score, 1 min, median (range) | 7.9 (4–9) | 8 (6–9) | NA | NA | NA |
| APGAR score, 5 min, median (range) | 8.8 (5–9) | 8.9 (8–9) | NA | NA | NA |
| Head circumference, median (range), cm | 33.99 (29–36) | 33.46 (29–35) | NA | 0.82§ | NA |
| PCR Zika virus–positive | 0 | 0 | 0 | NA | NA |
| Death or neonatal complications¶ | 5 (16) | 3 (5) | 8 (10) | 0.06 | 4.20 |
| Hyperbilirubinemia | 1 (3) | 2 (4) | 3 (4) | 0.90 | 1.10 |
| Intrauterine growth retardation | 0 | 2 (4) | 2 (2) | 0.47 | NA |
| Syphilis | 0 | 1 (2) | 1 (1) | 0.69 | NA |
| Gastroschisis | 1 (3) | 0 | 1 (1) | 0.31 | NA |
| Erythema toxicity | 2 (6) | 0 | 2 (2) | 0.09 | NA |
| Microcephaly | 0 | 1 (2) | 1 (1) | 0.69 | NA |
| Anemia | 0 | 1 (2) | 1 (1) | 0.69 | NA |
*Values are no. (%) unless otherwise indicated. NA, not applicable.
†By Fisher exact test.
‡Loss of follow-up for 5 Zika virus–positive mothers and for 10 Zika virus–negative mothers.
§By Wilcoxon signed-rank test.
¶Only 1 newborn death was observed and was from a Zika virus–positive mother.
Page created: July 15, 2019
Page updated: July 15, 2019
Page reviewed: July 15, 2019
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