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Volume 26, Number 10—October 2020
Research

Multicenter Prevalence Study Comparing Molecular and Toxin Assays for Clostridioides difficile Surveillance, Switzerland

Andreas F. Widmer, Reno Frei, Ed J. Kuijper, Mark H. Wilcox, Ruth Schindler, Violeta Spaniol, Daniel Goldenberger, Adrian Egli, Sarah Tschudin-SutterComments to Author , and Kuijper
Author affiliations: University Hospital Basel, Basel, Switzerland (A.F. Widmer, R. Frei, R. Schindler, V. Spaniol, D. Goldenberger, A. Egli, S. Tschudin-Sutter); Leiden University Medical Center, Leiden, the Netherlands (E.J. Kuijper); Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, and Leeds Teaching Hospitals, Leeds, UK (M.H. Wilcox)

Main Article

Table 1

Demographic data for 242 patients whose stool samples were included in the study of detection of Clostridioides difficile via PCR and enzyme immunoassay for glutamate dehydrogenase and A and B toxins, Switzerland*

Demographics All patients Method of Clostridioides difficile detection
EIA for GDH and A and B toxins, n = 21 PCR, n = 30
Median age, y (IQR)
63 (44–80)
79 (59–86)
78 (55–85)
Sex
M 104 (43.0) 6 (28.6) 10 (33.3)
F 131 (54.1) 15 (71.4) 20 (66.7)
Not reported
7 (2.9)
0
0
Clinical specialty
Medical 127 (52.5) 11 (52.4) 11 (36.7)
Surgery 43 (17.8) 3 (14.3) 6 (20.0)
Obstetrics, gynocology 3 (1.2) 0 0
Pediatrics 21 (8.7) 1 (4.8) 3 (10.0)
Other 28 (11.6) 5 (23.8) 7 (23.3)
Not reported 20 (8.3) 1 (4.8) 3 (10.0)
Intensive care 40 (16.5) 5 (23.8) 5 (16.7)

*Values are reported as no. (%) except where indicated. EIA, enzyme immunoassay; GDH, glutamate dehydrogenase; IQR, Interquartile range.

Main Article

Page created: July 24, 2020
Page updated: September 17, 2020
Page reviewed: September 17, 2020
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