Volume 26, Number 10—October 2020
Dispatch
Limitations of Ribotyping as Genotyping Method for Corynebacterium ulcerans
Table
Conserved mutation sites among strains 0102, 0211, and FH2016–1 of Corynebacterium ulcerans, Japan, 2001–2016*
Position (strain 0102) | Strain 0102 | Strain 0211 | FH2016–1 | Mutation type | Locus_tag, gene | ORF length, bp | Product | Detected mutation in each ORF | Amino acid substitution | Description |
---|---|---|---|---|---|---|---|---|---|---|
13,243 | T | TTC | T | Insertion | CULC0102_0011 | 705 | Putative membrane protein | 293T>TTC | NA | Pseudogene in strain 0211 |
147,936 | T | C | T | SNV | CULC0102_0143 | 873 | Putative ABC transporter, substrate binding protein | 476T>C | Leu159Ser | NA |
270,551 | AT | A | AT | Deletion | CULC0102_0261 | 3,204 | Putative surface-anchored membrane protein | 751AT>A | NA | Pseudogene in strain 0211 |
408,576 | C | T | C | SNV | CULC0102_0389 (menD) | 1,614 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | 1574C>T | Ala525Val | NA |
561,350 | A | AT | A | Insertion | CULC0102_0552 | 297 | Hypothetical protein | 218A>AT | NA | Pseudogene in strain 0211 |
820,419 | G | T | G | SNV | CULC0102_0788 | 5,073 | Putative helicase | 2928G>T | Lys976Asn | GO term: DNA metabolic process |
989,653 | C | T | C | SNV | CULC0102_0951 | 1,143 | Hypothetical protein | 965G>A | Gly322Asp | NA |
1,058,136 | G | A | G | SNV | CULC0102_1010 | 468 | Putative membrane protein | 88G>A | Gly30Ser | NA |
1,094,809 | T | C | T | SNV | CULC0102_1045 | 1,143 | Putative glutathione S-transferase | 55A>G | Thr19Ala | NA |
1,709,596 | G | T | G | SNV | CULC0102_1586 (trpC2) | 810 | Indole-3-glycerol phosphate synthase | 291C>A | His97Gln | NA |
1,886,000 | C | T | C | SNV | CULC0102_1749 (hrcA) | 1,047 | Heat-inducible transcription repressor | 232G>A | Val78Met | GO term: DNA metabolic process |
2,038,758 | GGC...GCA (123 bp) | G | GGC...GCA (123 bp) | Deletion | Intergenic_region | NA | NA | NA | NA | NA |
2,104,276 | G | A | G | SNV | CULC0102_1940 | 393 | Hypothetical protein | 346C>T | Arg116Cys | NA |
2,126,945 | C | T | C | SNV | CULC0102_1961 | 1,185 | Putative secreted esterase | 1072C>T | Arg358Stop | Pseudogene in strain 0211 |
2,401,441 | T | C | T | SNV | CULC0102_2194 (glf) | 1,197 | UDP-galactopyranose mutase | 80A>G | Asn27Ser | NA |
*NA, not applicable; ORF, open reading frame; SNV, single-nucleotide variation.
1Current affiliation: Osaka Prefecture University, Osaka, Japan.
Page created: July 28, 2020
Page updated: September 28, 2020
Page reviewed: September 28, 2020
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