Volume 26, Number 10—October 2020
Research
Association between Shiga Toxin–Producing Escherichia coli O157:H7 stx Gene Subtype and Disease Severity, England, 2009–2019
Lisa Byrne
, Natalie Adams, and Claire Jenkins
, Natalie Adams, and Claire Jenkins
Table 3
Univariate and multivariable regression analysis of disease severity for 3,225 patients with Shiga toxin–producing Escherichia coli O157:H7 infection, by isolate Stx subtype and patient age and sex, England, 2009–2019
| Category | Univariate |
Multivariable* |
||
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | p value | ||
| Stx subtype | ||||
| stx2c stx1a | 8.24 (6.53–10.40) | 7.89 (6.23–9.97) | <0.001 | |
| stx2c | Referent 1.00 | Referent | ||
| stx2a | 6.5 (5.10–8.28) | 7.04 (5.51–9.00) | <0.001 | |
| stx2a stx2c | 9.38 (7.38–11.91) | 10.12 (7.94–12.90) | <0.001 | |
| stx1a | 5.58 (2.69–11.58) | 5.44 (2.61–11.36) | <0.001 | |
| stx2a stx1a | 17.83 (8.48–37.51) | 19.45 (9.20–41.16) | <0.001 | |
| stx2a stx2c stx1a |
16.98 (8.05–35.83) |
17.38 (8.20–36.86) |
<0.001 |
|
| Age group | ||||
| Adult | Referent 1.00 | Referent | ||
| Child |
0.61 (0.3–0.70) |
0.56 (0.48–0.66) |
<0.001 |
|
| Sex | ||||
| M | Referent 1.00 | Referent | ||
| F | 1.14 (0.99–1.31) | 1.09 (0.93–1.27) | 0.286 | |
*Adjusted for all other covariates in the model.
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