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Volume 26, Number 10—October 2020
Research Letter

Relative Bradycardia in Patients with Mild-to-Moderate Coronavirus Disease, Japan

Kazuhiko Ikeuchi, Makoto Saito, Shinya Yamamoto, Hiroyuki Nagai, and Eisuke AdachiComments to Author 
Author affiliations: The University of Tokyo, Tokyo, Japan

Main Article

Table

Characteristics of patients with relative bradycardia and mild-to-moderate coronavirus disease, Japan

Characteristic No. assessed Value*
Age, y
54
45.5 (20–81)
Sex
M 39 39 (72.2)
F
15
15 (27.8)
Body mass index, kg/m2 54 23.7 (15.9–51.1)
Current smoker 48 16 (33.3)
Days from symptom onset to admission
54
9 (2–25)
Vital signs at admission
Body temperature, °C 54 37.2 (36.1–39.2)
Pulse rate, beats/min 54 84 (62–134)
Systolic blood pressure, mm Hg 54 116 (80–170)
Diastolic blood pressure, mm Hg 54 70.5 (51–124)
Respiratory rate, breaths/min 53 18 (16–26)
Percutaneous oxygen saturation, %†
54
97 (92–100)
Highest temperature during admission,°C 54
<37.5 54 27 (50.0)
37.5–38.9 54 20 (37.0)
>38.9°C
54
7 (13.0)
Laboratory findings at admission
Leukocyte count, cells/mm3 54 5,530 (2,690–16,700)
Lymphocyte count, cells/mm3 54 1,251 (381–2,852)
Hemoglobin, g/dL 54 14.7 (11.1–17.3)
Platelet count, × 1,000/mm3 54 231 (106–444)
Blood urea nitrogen, mmol/L 54 4.3 (2.1–7.9)
Creatinine, μmol/L 54 69.0 (34.5–120.2)
Sodium, mmol/L 53 139 (132–148)
Potassium, mmol/L 53 4.0 (3.1–4.8)
Creatine kinase, U/L 52 74 (22–674)
C-reactive protein, mg/L 54 17.9 (0.1–215.6)
Brain natriuretic peptide, pg/mL 52 5.8 (5.8–43.2)
D-dimer, mg/L
50
0.5 (0.5–6.5)
Concurrent conditions
Hypertension 54 8 (14.8)
Diabetes 54 5 (9.3)
Chronic obstructive pulmonary disease 54 1 (1.9)
Coronary heart disease 54 0 (0)
HIV Infection 54 4 (7.4)

*Values are median (range) or no. (%).
†Nine patients required oxygen therapy at admission.

Main Article

Page created: June 29, 2020
Page updated: September 17, 2020
Page reviewed: September 17, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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