Volume 26, Number 11—November 2020
Research
Systematic Review and Meta-Analyses of Incidence for Group B Streptococcus Disease in Infants and Antimicrobial Resistance, China
Yijun Ding, Yajuan Wang
, Yingfen Hsia, Neal Russell, and Paul T. Heath
, Yingfen Hsia, Neal Russell, and Paul T. Heath
Table 1
Characteristics of included studies and outcome types for systematic review and meta-analyses of incidence of group B Streptococcus disease in infants, China*
| Characteristic | Type and no. studies |
|||||
|---|---|---|---|---|---|---|
| Total, 64 | Incidence, 14 | CFR, 56 | AMR, 20 | Serotypes, 4 | MLST, 2 | |
| China | ||||||
| Eastern | 59 | 13 | 52 | 19 | 4 | 2 |
| Central | 2 | 0 | 2 | 0 | 0 | 0 |
| Western | 2 | 1 | 2 | 0 | 0 | 0 |
| Northeastern |
1 |
0 |
0 |
1 |
0 |
0 |
| Hospital type | ||||||
| Mainland China | ||||||
| Tertiary | 45 | 6 | 39 | 18 | 4 | 2 |
| Secondary | 9 | 3 | 9 | 2 | 0 | 0 |
| Primary | 1 | 0 | 1 | 0 | 0 | 0 |
| Nonmainland China | 0 | |||||
| Teaching | 8 | 4 | 7 | 0 | 0 | 0 |
| General |
1 |
1 |
0 |
0 |
0 |
0 |
| Study design | ||||||
| Prospective | 4 | 3 | 3 | 0 | 1 | 1 |
| Retrospective |
60 |
11 |
53 |
20 |
3 |
1 |
| Reporting period, days | ||||||
| Full, 0–89 | 53 | 11 | 46 | 16 | 4 | 2 |
| Full EOGBS <1–6 | 7 | 3 | 6 | 2 | 0 | 0 |
| Full LOGBS 7–89 |
4 |
0 |
4 |
2 |
0 |
0 |
| Specimen type | ||||||
| Blood only | 25 | 5 | 18 | 8 | 2 | 0 |
| CSF only | 6 | 0 | 6 | 3 | 0 | 0 |
| Blood and CSF | 23 | 6 | 22 | 9 | 2 | 2 |
| All sterile sites | 4 | 3 | 3 | 0 | 0 | 0 |
| Blood and CSF plus sputum or gastric fluid |
6 |
0 |
7 |
0 |
0 |
0 |
| IAP | ||||||
| Any | 10 | 6 | 9 | 3 | 1 | 1 |
| None | 4 | 0 | 3 | 2 | 0 | 0 |
| Unknown | 50 | 8 | 44 | 15 | 3 | 1 |
*AMR, antimicrobial resistance; CFR, case-fatality rate; CSF, cerebrospinal fluid; EOGBS, early onset group B Streptococcus; IAP, intrapartum antimicrobial drug prophylaxis; MLST, multilocus sequence typing; LOGBS, late onset group B Streptococcus.
Page created: August 17, 2020
Page updated: October 17, 2020
Page reviewed: October 17, 2020
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