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Volume 26, Number 11—November 2020
Research

Systematic Review and Meta-Analyses of Incidence for Group B Streptococcus Disease in Infants and Antimicrobial Resistance, China

Yijun Ding, Yajuan WangComments to Author , Yingfen Hsia, Neal Russell, and Paul T. Heath
Author affiliations: National Center for Children’s Health, Beijing, China (Y. Ding, Y. Wang); University of London, London, UK (Y. Hsia, N. Russell, P.T. Heath); Queen’s University Belfast, Belfast, Northern Ireland, UK (Y. Hsia)

Main Article

Table 1

Characteristics of included studies and outcome types for systematic review and meta-analyses of incidence of group B Streptococcus disease in infants, China*

Characteristic Type and no. studies
Total, 64 Incidence, 14 CFR, 56 AMR, 20 Serotypes, 4 MLST, 2
China
Eastern 59 13 52 19 4 2
Central 2 0 2 0 0 0
Western 2 1 2 0 0 0
Northeastern
1
0
0
1
0
0
Hospital type
Mainland China
Tertiary 45 6 39 18 4 2
Secondary 9 3 9 2 0 0
Primary 1 0 1 0 0 0
Nonmainland China 0
Teaching 8 4 7 0 0 0
General
1
1
0
0
0
0
Study design
Prospective 4 3 3 0 1 1
Retrospective
60
11
53
20
3
1
Reporting period, days
Full, 0–89 53 11 46 16 4 2
Full EOGBS <1–6 7 3 6 2 0 0
Full LOGBS 7–89
4
0
4
2
0
0
Specimen type
Blood only 25 5 18 8 2 0
CSF only 6 0 6 3 0 0
Blood and CSF 23 6 22 9 2 2
All sterile sites 4 3 3 0 0 0
Blood and CSF plus sputum or gastric fluid
6
0
7
0
0
0
IAP
Any 10 6 9 3 1 1
None 4 0 3 2 0 0
Unknown 50 8 44 15 3 1

*AMR, antimicrobial resistance; CFR, case-fatality rate; CSF, cerebrospinal fluid; EOGBS, early onset group B Streptococcus; IAP, intrapartum antimicrobial drug prophylaxis; MLST, multilocus sequence typing; LOGBS, late onset group B Streptococcus.

Main Article

Page created: August 17, 2020
Page updated: October 17, 2020 10:07 PM EDT
Page reviewed: October 17, 2020 10:07 PM EDT
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