Volume 26, Number 12—December 2020
Online Report
Role of Oral Rabies Vaccines in the Elimination of Dog-Mediated Human Rabies Deaths
Table 1
Successful vaccination programs |
Unsuccessful vaccination programs |
|||||
---|---|---|---|---|---|---|
Country | Vaccination coverage, % | Reference | Country | Vaccination coverage, % | Reference | |
Zambia | 80 | (29) | Chad | 19 | (30) | |
Mexico | >90 | (31) | Chad | 24 | (32) | |
Chad | 74 | (30) | Kenya | 29 | (33) | |
Thailand | 70 | (34) | Nigeria | 17 | (35) | |
Bolivia | 85 | (36) | South Africa | 56 | (37) | |
Tanzania | 68 | (38) | Tanzania | 9 | (38) |
References
- World Health Organization. Ten years in public health, 2007–2017. Geneva: The Organization; 2017.
- World Health Organization. Global programme to eliminate lymphatic filariasis: progress report, 2016. Wkly Epidemiol Rec. 2017;92:594–607.PubMedGoogle Scholar
- Greene SA, Ahmed J, Datta SD, Burns CC, Quddus A, Vertefeuille JF, et al. Progress toward polio eradication—worldwide, January 2017–March 2019. MMWR Morb Mortal Wkly Rep. 2019;68:458–62. DOIPubMedGoogle Scholar
- The Lancet. Guinea worm disease eradication: a moving target. Lancet. 2019;393:1261. DOIPubMedGoogle Scholar
- Njeumi F, Taylor W, Diallo A, Miyagishima K, Pastoret PP, Vallat B, et al. The long journey: a brief review of the eradication of rinderpest. Rev Sci Tech. 2012;31:729–46. DOIPubMedGoogle Scholar
- Minghui R, Stone M, Semedo MH, Nel L. New global strategic plan to eliminate dog-mediated rabies by 2030. Lancet Glob Health. 2018;6:e828–9. DOIPubMedGoogle Scholar
- Wallace RM, Undurraga EA, Blanton JD, Cleaton J, Franka R. Elimination of dog-mediated human rabies deaths by 2030: needs assessment and alternatives for progress based on dog vaccination. Front Vet Sci. 2017;4:9. DOIPubMedGoogle Scholar
- World Health Organization. Zero by 30: the global strategic plan to prevent human deaths from dog-transmitted rabies by 2030—executive summary. 2018 [cited 2018 Jun 20]. http://www.oie.int/fileadmin/Home/eng/Media_Center/docs/pdf/Rabies_portal/EN_executiveSummary.pdf
- World Health Organization. WHO expert consultation on rabies: third report. World Health Organ Tech Rep Ser. 2018;1012:195 [cited 2019 Dec 10]. https://apps.who.int/iris/handle/10665/272364
- Rupprecht CE, Barrett J, Briggs D, Cliquet F, Fooks AR, Lumlertdacha B, et al. Can rabies be eradicated? Dev Biol (Basel). 2008;131:95–121.PubMedGoogle Scholar
- Fooks AR, Banyard AC, Horton DL, Johnson N, McElhinney LM, Jackson AC. Current status of rabies and prospects for elimination. Lancet. 2014;384:1389–99. DOIPubMedGoogle Scholar
- World Health Organization. WHO expert consultation on rabies: second report. World Health Organ Tech Rep Ser. 2013;982:1–139.PubMedGoogle Scholar
- Hampson K, Coudeville L, Lembo T, Sambo M, Kieffer A, Attlan M, et al.; Global Alliance for Rabies Control Partners for Rabies Prevention. Estimating the global burden of endemic canine rabies. PLoS Negl Trop Dis. 2015;9:
e0003709 . DOIPubMedGoogle Scholar - Shwiff SA, Elser JL, Ernst KH, Shwiff SS, Anderson AM. Cost-benefit analysis of controlling rabies: placing economics at the heart of rabies control to focus political will. Rev Sci Tech. 2018;37:681–9. DOIPubMedGoogle Scholar
- Müller T, Demetriou P, Moynagh J, Cliquet F, Fooks AR, Conraths FJ, et al. Rabies elimination in Europe—a success story. In: Fooks AR, Müller T, editors. Rabies control—towards sustainable prevention at the source: compendium of the OIE Global Conference on Rabies Control, Incheon-Seoul, South Korea, 7–9 Sep 2011. Paris: World Organization for Animal Health; 2012. p. 31–44.
- Velasco-Villa A, Escobar LE, Sanchez A, Shi M, Streicker DG, Gallardo-Romero NF, et al. Successful strategies implemented towards the elimination of canine rabies in the Western Hemisphere. Antiviral Res. 2017;143:1–12. DOIPubMedGoogle Scholar
- Clavijo A, Del Rio Vilas VJ, Mayen FL, Yadon ZE, Beloto AJ, Vigilato MA, et al. Gains and future road map for the elimination of dog-transmitted rabies in the Americas. Am J Trop Med Hyg. 2013;89:1040–2. DOIPubMedGoogle Scholar
- Vigilato MA, Clavijo A, Knobl T, Silva HM, Cosivi O, Schneider MC, et al. Progress towards eliminating canine rabies: policies and perspectives from Latin America and the Caribbean. Philos Trans R Soc Lond B Biol Sci. 2013;368:
20120143 . DOIPubMedGoogle Scholar - Lapiz SM, Miranda ME, Garcia RG, Daguro LI, Paman MD, Madrinan FP, et al. Implementation of an intersectoral program to eliminate human and canine rabies: the Bohol Rabies Prevention and Elimination Project. PLoS Negl Trop Dis. 2012;6:
e1891 . DOIPubMedGoogle Scholar - Kayali U, Mindekem R, Hutton G, Ndoutamia AG, Zinsstag J. Cost-description of a pilot parenteral vaccination campaign against rabies in dogs in N’Djaména, Chad. Trop Med Int Health. 2006;11:1058–65. DOIPubMedGoogle Scholar
- World Health Organization. Mexico is free from human rabies transmitted by dogs. 2019 [cited 2019 Dec 28]. https://www.who.int/news/item/21-12-2019-mexico-is-free-from-human-rabies-transmitted-by-dogs
- Knobel DL, Cleaveland S, Coleman PG, Fèvre EM, Meltzer MI, Miranda ME, et al. Re-evaluating the burden of rabies in Africa and Asia. Bull World Health Organ. 2005;83:360–8.PubMedGoogle Scholar
- Freuling CM, Hampson K, Selhorst T, Schröder R, Meslin FX, Mettenleiter TC, et al. The elimination of fox rabies from Europe: determinants of success and lessons for the future. Philos Trans R Soc Lond B Biol Sci. 2013;368:
20120142 . DOIPubMedGoogle Scholar - MacInnes CD, Smith SM, Tinline RR, Ayers NR, Bachmann P, Ball DG, et al. Elimination of rabies from red foxes in eastern Ontario. J Wildl Dis. 2001;37:119–32. DOIPubMedGoogle Scholar
- Slate D, Algeo TP, Nelson KM, Chipman RB, Donovan D, Blanton JD, et al. Oral rabies vaccination in north america: opportunities, complexities, and challenges. PLoS Negl Trop Dis. 2009;3:
e549 . DOIPubMedGoogle Scholar - Robardet E, Bosnjak D, Englund L, Demetriou P, Martín PR, Cliquet F. Zero endemic cases of wildlife rabies (classical rabies virus, RABV) in the European Union by 2020: an achievable goal. Trop Med Infect Dis. 2019;4:124. DOIPubMedGoogle Scholar
- Cliquet F, Guiot AL, Aubert M, Robardet E, Rupprecht CE, Meslin FX. Oral vaccination of dogs: a well-studied and undervalued tool for achieving human and dog rabies elimination. Vet Res (Faisalabad). 2018;49:61. DOIPubMedGoogle Scholar
- De Balogh KK, Wandeler AI, Meslin FX. A dog ecology study in an urban and a semi-rural area of Zambia. Onderstepoort J Vet Res. 1993;60:437–43.PubMedGoogle Scholar
- Kayali U, Mindekem R, Yémadji N, Vounatsou P, Kaninga Y, Ndoutamia AG, et al. Coverage of pilot parenteral vaccination campaign against canine rabies in N’Djaména, Chad. Bull World Health Organ. 2003;81:739–44.PubMedGoogle Scholar
- Vigilato MA, Clavijo A, Knobl T, Silva HM, Cosivi O, Schneider MC, et al. Progress towards eliminating canine rabies: policies and perspectives from Latin America and the Caribbean. Philos Trans R Soc Lond B Biol Sci. 2013;368:
20120143 . DOIPubMedGoogle Scholar - Durr S, Mindekem R, Kaninga Y, Doumagoum Moto D, Meltzer MI, Vounatsou P, et al. Effectiveness of dog rabies vaccination programmes: comparison of owner-charged and free vaccination campaigns. Epidemiol Infect. 2009;137:1558–67. DOIPubMedGoogle Scholar
- Kitala P, McDermott J, Kyule M, Gathuma J, Perry B, Wandeler A. Dog ecology and demography information to support the planning of rabies control in Machakos District, Kenya. Acta Trop. 2001;78:217–30. DOIPubMedGoogle Scholar
- Kongkaew W, Coleman P, Pfeiffer DU, Antarasena C, Thiptara A. Vaccination coverage and epidemiological parameters of the owned-dog population in Thungsong District, Thailand. Prev Vet Med. 2004;65:105–15. DOIPubMedGoogle Scholar
- Dzikwi AA, Ibrahim AS, Umoh JU. Knowledge, attitude and practice about rabies among children receiving formal and informal education in Samaru, Zaria, Nigeria. Glob J Health Sci. 2012;4:132–9. DOIPubMedGoogle Scholar
- Suzuki K, Pereira JA, Frías LA, López R, Mutinelli LE, Pons ER. Rabies-vaccination coverage and profiles of the owned-dog population in Santa Cruz de la Sierra, Bolivia. Zoonoses Public Health. 2008;55:177–83. DOIPubMedGoogle Scholar
- van Sittert SJ, Raath J, Akol GW, Miyen JM, Mlahlwa B, Sabeta CT. Rabies in the Eastern Cape Province of South Africa—where are we going wrong? J S Afr Vet Assoc. 2010;81:207–15. DOIPubMedGoogle Scholar
- Cleaveland S, Kaare M, Tiringa P, Mlengeya T, Barrat J. A dog rabies vaccination campaign in rural Africa: impact on the incidence of dog rabies and human dog-bite injuries. Vaccine. 2003;21:1965–73. DOIPubMedGoogle Scholar
- Lembo T, Hampson K, Kaare MT, Ernest E, Knobel D, Kazwala RR, et al. The feasibility of canine rabies elimination in Africa: dispelling doubts with data. PLoS Negl Trop Dis. 2010;4:
e626 . DOIPubMedGoogle Scholar - Adrien J, Georges Y, Augustin PD, Monroe B, Gibson AD, Fenelon N, et al.; Haiti-Rabies Field Response Team. A multipartner response to prevent a binational rabies outbreak—Anse-à-Pitre, Haiti, 2019. MMWR Morb Mortal Wkly Rep. 2019;68:707–9. DOIPubMedGoogle Scholar
- Gibson AD, Ohal P, Shervell K, Handel IG, Bronsvoort BM, Mellanby RJ, et al. Vaccinate-assess-move method of mass canine rabies vaccination utilising mobile technology data collection in Ranchi, India. BMC Infect Dis. 2015;15:589. DOIPubMedGoogle Scholar
- Gibson AD, Yale G, Vos A, Corfmat J, Airikkala-Otter I, King A, et al. Oral bait handout as a method to access roaming dogs for rabies vaccination in Goa, India: A proof of principle study. Vaccine X. 2019;1:
100015 . DOIPubMedGoogle Scholar - Purwo Suseno P, Rysava K, Brum E, De Balogh K, Ketut Diarmita I, Fakhri Husein W, et al. Lessons for rabies control and elimination programmes: a decade of One Health experience from Bali, Indonesia. Rev Sci Tech. 2019;38:213–24. DOIPubMedGoogle Scholar
- Gibson AD, Wallace RM, Rahman A, Bharti OK, Isloor S, Lohr F, et al. Reviewing solutions of scale for canine rabies elimination in India. Trop Med Infect Dis. 2020;5:47. DOIPubMedGoogle Scholar
- Smith TG, Millien M, Vos A, Fracciterne FA, Crowdis K, Chirodea C, et al. Evaluation of immune responses in dogs to oral rabies vaccine under field conditions. Vaccine. 2019;37:4743–9.PubMedGoogle Scholar
- Wallace RM, Undurraga EA, Gibson A, Boone J, Pieracci EG, Gamble L, et al. Estimating the effectiveness of vaccine programs in dog populations. Epidemiol Infect. 2019;147:
e247 .PubMedGoogle Scholar - Ben Youssef S, Matter HC, Schumacher CL, Kharmachi H, Jemli J, Mrabet L, et al. Field evaluation of a dog owner, participation-based, bait delivery system for the oral immunization of dogs against rabies in Tunisia. Am J Trop Med Hyg. 1998;58:835–45.PubMedGoogle Scholar
- Matter HC, Kharmachi H, Haddad N, Ben Youssef S, Sghaier C, Ben Khelifa R, et al. Test of three bait types for oral immunization of dogs against rabies in Tunisia. Am J Trop Med Hyg. 1995;52:489–95.PubMedGoogle Scholar
- World Health Organization. Report of WHO consultation on oral immunization of dogs against rabies. Geneva: The Organization; 1988 [cited 2019 Dec 10]. https://apps.who.int/iris/handle/10665/58694
- World Health Organization. Report of WHO consultation on requirements and criteria for field trials on oral rabies vaccination of dogs and wild carnivores. Geneva: The Organization; 1989 [cited 2019 Dec 10]. https://apps.who.int/iris/handle/10665/58394
- World Health Organization. Oral vaccination of dogs against rabies—guidance for research on oral rabies vaccines and field application of oral vaccination of dogs against rabies. Geneva, The Organization; 2007 [cited 2019 Dec 10]. https://apps.who.int/iris/handle/10665/331036
- World Organization for Animal Health. Rabies (infection with rabies virus and other lyssaviruses) [chapter 3.1.17]. In: Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Meslin F-X, editor. Paris: World Organization for Animal Health; 2018. p. 35 [cited 2019 Dec 10]. https://apps.who.int/iris/handle/10665/331036
- Cliquet F, Guiot AL, Aubert M, Robardet E, Rupprecht CE, Meslin FX. Correction to: Oral vaccination of dogs: a well-studied and undervalued tool for achieving human and dog rabies elimination. Vet Res. 2018;49:84.PubMedGoogle Scholar
- Fu R, Altamirano J, Sarnquist CC, Maldonado YA, Andrews JR. Assessing the risk of vaccine-derived outbreaks after reintroduction of oral poliovirus vaccine in postcessation settings. Clin Infect Dis. 2018;67(suppl_1):S26–34.
- Medaglia ML, Pessoa LC, Sales ER, Freitas TR, Damaso CR. Spread of cantagalo virus to northern Brazil. Emerg Infect Dis. 2009;15:1142–3.PubMedGoogle Scholar
- Rupprecht CE, Blass L, Smith K, Orciari LA, Niezgoda M, Whitfield SG, et al. Human infection due to recombinant vaccinia-rabies glycoprotein virus. N Engl J Med. 2001;345:582–6. DOIPubMedGoogle Scholar
- Centers for Disease Control and Prevention (CDC). Human vaccinia infection after contact with a raccoon rabies vaccine bait - Pennsylvania, 2009. MMWR Morb Mortal Wkly Rep. 2009;58:1204–7.PubMedGoogle Scholar
- Müller T, Bätza HJ, Beckert A, Bunzenthal C, Cox JH, Freuling CM, et al. Analysis of vaccine-virus-associated rabies cases in red foxes (Vulpes vulpes) after oral rabies vaccination campaigns in Germany and Austria. Arch Virol. 2009;154:1081–91. DOIPubMedGoogle Scholar
- Hostnik P, Picard-Meyer E, Rihtarič D, Toplak I, Cliquet F. Vaccine-induced rabies in a red fox (Vulpes vulpes): isolation of vaccine virus in brain tissue and salivary glands. J Wildl Dis. 2014;50:397–401. DOIPubMedGoogle Scholar
- Vuta V, Picard-Meyer E, Robardet E, Barboi G, Motiu R, Barbuceanu F, et al. Vaccine-induced rabies case in a cow (Bos taurus): Molecular characterisation of vaccine strain in brain tissue. Vaccine. 2016;34:5021–5. DOIPubMedGoogle Scholar
- Wandeler AI, Capt S, Kappeler A, Hauser R. Oral immunization of wildlife against rabies: concept and first field experiments. Rev Infect Dis. 1988;10(Suppl 4):S649–53. DOIPubMedGoogle Scholar
- Fehlner-Gardiner C, Nadin-Davis S, Armstrong J, Muldoon F, Bachmann P, Wandeler A. Era vaccine-derived cases of rabies in wildlife and domestic animals in Ontario, Canada, 1989-2004. J Wildl Dis. 2008;44:71–85. DOIPubMedGoogle Scholar
- Pfaff F, Müller T, Freuling CM, Fehlner-Gardiner C, Nadin-Davis S, Robardet E, et al. In-depth genome analyses of viruses from vaccine-derived rabies cases and corresponding live-attenuated oral rabies vaccines. Vaccine. 2019;37:4758–65. DOIPubMedGoogle Scholar
- Electronic Code of Federal Regulations. Title 9, subchapter E, part 113. Standard requirements, subjgrp 74: live virus vaccines. 2007 [cited 2019 Dec 10]. https://www.ecfr.gov/cgi-bin/text-idx?tpl=/ecfrbrowse/Title09/9cfrv1_02.tpl
- European Directorate for the Quality of Medicines. Rabies vaccine (live, oral) for foxes and raccoon dogs. Strasbourg (France): European Council; 2014. p. 1011–2.
- Head JR, Vos A, Blanton J, Müller T, Chipman R, Pieracci EG, et al. Environmental distribution of certain modified live-virus vaccines with a high safety profile presents a low-risk, high-reward to control zoonotic diseases. Sci Rep. 2019;9:6783. DOIPubMedGoogle Scholar
- Dellepiane N, Wood D. Twenty-five years of the WHO vaccines prequalification programme (1987-2012): lessons learned and future perspectives. Vaccine. 2015;33:52–61. DOIPubMedGoogle Scholar
- Gibson AD, Mazeri S, Yale G, Desai S, Naik V, Corfmat J, et al. Development of a non-meat-based, mass producible and effective bait for oral vaccination of dogs against rabies in Goa State, India. Trop Med Infect Dis. 2019;4:118. DOIPubMedGoogle Scholar
- World Organization for Animal Health. OIE policy paper on vaccine banks. Paris: World Organization for Animal Health; 2018. p. 16 [cited 2019 Dec 10]. https://www.oie.int/fileadmin/Home/eng/Links/docs/pdf/Policy-Paper-VB-final-EN_Oct-2018_01.pdf
- Mace J, Renaudin S, Dieuzy-Labaye I, Dehove A. Vaccine banks for controlling dog-mediated rabies. Rev Sci Tech. 2018;37:511–8. DOIPubMedGoogle Scholar
- Jeon S, Cleaton J, Meltzer MI, Kahn EB, Pieracci EG, Blanton JD, et al. Determining the post-elimination level of vaccination needed to prevent re-establishment of dog rabies. PLoS Negl Trop Dis. 2019;13:
e0007869 . DOIPubMedGoogle Scholar - Anderson A, Kotzé J, Shwiff SA, Hatch B, Slootmaker C, Conan A, et al. A bioeconomic model for the optimization of local canine rabies control. PLoS Negl Trop Dis. 2019;13:
e0007377 . DOIPubMedGoogle Scholar - Borse RH, Atkins CY, Gambhir M, Undurraga EA, Blanton JD, Kahn EB, et al. Cost-effectiveness of dog rabies vaccination programs in East Africa. PLoS Negl Trop Dis. 2018;12:
e0006490 . DOIPubMedGoogle Scholar - Darkaoui S, Cliquet F, Wasniewski M, Robardet E, Aboulfidaa N, Bouslikhane M, et al. A century spent combating rabies in Morocco (1911–2015): how much longer? Front Vet Sci. 2017;4:78. DOIPubMedGoogle Scholar
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