Role of Oral Rabies Vaccines in the Elimination of Dog-Mediated Human Rabies Deaths
Ryan M. Wallace
, Florence Cliquet, Christine Fehlner-Gardiner, Anthony R. Fooks, Claude T. Sabeta, Alvaro Aguilar Setién, Changchun Tu, Vlad Vuta, Boris Yakobson, Dong-Kun Yang, Gideon Brückner, Conrad M. Freuling, Lea Knopf, Artem Metlin, Patricia Pozzetti, Pebi Purwo Suseno, Sean V. Shadomy, Gregorio Torres, Marco Antonio Natal Vigilato, Bernadette Abela-Ridder, and Thomas Müller
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (R.M. Wallace, S.V. Shadomy); Agency for Food, Environmental, and Occupational Health and Safety, Malzéville, France (F. Cliquet); Canadian Food Inspection Agency, Ottawa, Ontario, Canada (C. Fehlner-Gardiner); Animal and Plant Health Agency, Weybridge, UK (A.R. Fooks); Onderstepoort Veterinary Institute, Pretoria, South Africa (C.T. Sabeta); Unidad de Investigación Médica en Inmunología, Coordinación de Investigación en Salud, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico (A.A. Setién); Academy of Agricultural Sciences, Changchun, China (C. Tu); Institute for Diagnosis and Animal Health, Faculty of Veterinary Medicine, Bucharest, Romania (V. Vuta); Kimron Veterinary Institute, Beit Dagan, Israel (B. Yakobson); Animal and Plant Quarantine Agency, Gimcheong-si, South Korea (D.-K. Yang); World Organisation for Animal Health, Paris, France (G. Brückner, P. Pozzetti, G. Torres); Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany (C.M. Freuling, T. Müller); World Health Organization, Geneva, Switzerland (L. Knopf, B. Abela-Ridder); Federal Centre for Animal Health, Vladimir, Russia (A. Metlin); Ministry of Agriculture, Jakarta, Indonesia (P. Purwo Suseno); Food and Agriculture Organization of the United Nations, Rome, Italy (S.V. Shadomy); Pan American Health Organization, Rio de Janeiro, Brazil (M.A.N. Vigilato)
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Table 4
Considerations for rabies vaccination methods applied to dog populations
Accessibility of the dog population |
Central point |
Door-to-door |
Capture–vaccinate–release |
Oral vaccination |
Owned, confined dogs |
Good coverage |
Good coverage |
Moderate coverage |
Rarely applicable* |
Owned, roaming dogs |
Moderate coverage |
Moderate coverage |
Good coverage |
Good coverage |
Unowned dogs |
Poor coverage |
Poor coverage |
Good coverage |
Good coverage |
Advantage |
Inexpensive |
Owners do not have to transport dogs |
Expensive and requires trained staff |
Easy and targets free roaming dogs |
Disadvantage |
Low free-roaming dog coverage |
Low free-roaming dog coverage |
Cost and scalability concerns |
Cost, safety, and efficacy concerns |
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Page created: October 15, 2020
Page updated: November 19, 2020
Page reviewed: November 19, 2020
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