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Volume 26, Number 12—December 2020
Dispatch

Susceptibility of Raccoon Dogs for Experimental SARS-CoV-2 Infection

Conrad M. Freuling1Comments to Author , Angele Breithaupt1, Thomas Müller, Julia Sehl, Anne Balkema-Buschmann, Melanie Rissmann, Antonia Klein, Claudia Wylezich, Dirk Höper, Kerstin Wernike, Andrea Aebischer, Donata Hoffmann, Virginia Friedrichs, Anca Dorhoi, Martin H. Groschup, Martin Beer, and Thomas C. Mettenleiter
Author affiliation: Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

Main Article

Table

Serologic response of raccoon dogs to experimental SARS-CoV-2 infection, by day after inoculation*

Animal no. Day 8
 Day 12
 Day 16
 Day 21
 Day 28
iIFA VNT iIFA VNT iIFA VNT iIFA VNT iIFA VNT
Inoculated
1
2
3 1:128 <1:4
4 <1:20 <1:2
5 1:64 <1:2 1:64 <1:2
6 1:128 1:5.04 1:64 1:12.7
7 1:128 <1:4 1:64 <1:2 1:64 1:4 1:128 1:10.08 1:1,024 1:12.7
8 <1:20 <1:2 <1:20 <1:2 <1:20 <1:2 <1:20 <1:2 <1:20 <1:2
9
 <1:20
 <1:2
<1:20
 <1:2
<1:20
 <1:2
<1:20
 <1:2
<1:20
 <1:2
In-contact
10 <1:20 <1:2 <1:20 <1:2 1:64 <1:2 1:128 <1:4 1:512 <1:4
11 <1:20 <1:2 <1:20 <1:2 1:64 <1:2 1:128 1:5.04 1:256 <1:4
12 <1:20 <1:2 <1:20 <1:2 <1:20 <1:2 <1:20 <1:2 <1:20 <1:2

*No serologic response recorded for days 0 and 4. Animal nos. 4, 8, and 9 did not show signs of infection. Each day, 2 raccoon dogs were euthanized and autopsied. iIFA, indirect immunofluorescence assay; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; VNT, virus neutralization test.

Main Article

1These first authors contributed equally to this article.

Page created: September 23, 2020
Page updated: November 19, 2020
Page reviewed: November 19, 2020
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