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Volume 26, Number 3—March 2020
Research

Randomized Trial of 2 Schedules of Meningococcal B Vaccine in Adolescents and Young Adults, Canada1

Joanne M. LangleyComments to Author , Soren Gantt, Caroline Quach, Julie A. Bettinger, Scott A. Halperin, Jill Mutch, Shelly A. McNeil, Brian J. Ward, Donna MacKinnon-Cameron, Lingyun Ye, Kim Marty, David Scheifele, Erin Brown, Joenel Alcantara, and The Canadian Immunization Research Network
Author affiliations: Canadian Center for Vaccinology, Dalhousie University, IWK Health Centre, and Nova Scotia Health Authority, Halifax, Nova Scotia, Canada (J.M. Langley, S.A. Halperin, J. Mutch, S.A. McNeil, D. MacKinnon-Cameron, L. Ye); Vaccine Evaluation Center, University of British Columbia, Vancouver, British Columbia, Canada (S. Gantt, J.A. Bettinger, K. Marty, D. Scheifele); University of Montreal, Montreal, Quebec, Canada (C. Quach); Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada (C. Quach, B.J. Ward); University of Calgary, Calgary, Alberta, Canada (E. Brown, J. Alcantara)

Main Article

Figure 4

Percent of participants reporting solicited local and systemic adverse events on day 0 and day 8 after each vaccine dose in trial of 4-component protein-based meningococcal B vaccine, Canada. A-C) Adverse events localized at injection site. D-F) General adverse events. Grade 1: mild, easily tolerated by participant; grade 2: moderate, sufficiently discomforting to interfere with normal everyday activities; grade 3: severe, prevents normal, everyday activities. Error bars indicate 95% CIs.

Figure 4. Percent of participants reporting solicited local and systemic adverse events on day 0 and day 8 after each vaccine dose in trial of 4-component protein-based meningococcal B vaccine, Canada. A-C) Adverse events localized at injection site. D-F) General adverse events. Grade 1: mild, easily tolerated by participant; grade 2: moderate, sufficiently discomforting to interfere with normal everyday activities; grade 3: severe, prevents normal, everyday activities. Error bars indicate 95% CIs.

Main Article

1Preliminary results from this study were presented at IDWeek, October 26–30, 2016, New Orleans, LA, USA; and at the Meningitis Research Foundation Conference, November 14–15, 2017, London, England, UK.

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