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Volume 26, Number 3—March 2020
Research

Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Beijing Clades, Ukraine, 2015

Matthias MerkerComments to Author , Elena Nikolaevskaya, Thomas A. Kohl, Barbara Molina-Moya, Olha Pavlovska, Patrik Brännberg, Andrii Dudnyk, Valentyna Stokich, Ivan Barilar, Iryna Marynova, Tetiana Filipova, Cristina Prat, Anders Sjöstedt, Jose Dominguez, Olena RzhepishevskaComments to Author , and Stefan Niemann
Author affiliations: Research Center Borstel, Borstel, Germany (M. Merker, T.A. Kohl, I. Barilar, S. Niemann); Odessa Regional TB Hospital, Odessa, Ukraine (E. Nikolaevskaya, O. Pavlovska, V. Stokich); Institut d'Investigació Germans Trias i Pujol, Badalona, Spain (B. Molina-Moya, C. Prat, J. Dominguez); Centro de Investigación Biomédica en Red (CIBERES), Badalona (B. Molina-Moya, C. Prat, J. Dominguez); Universitat Autònoma de Barcelona, Barcelona, Spain (B. Molina-Moya, C. Prat, J. Dominguez); Umeå University, Umea, Sweden (P. Brännberg, A. Sjöstedt, O. Rzhepishevska); National Pirogov Memorial Medical University, Vinnytsia, Ukraine (A. Dudnyk); Odessa I.I. Mechnikov National University, Odessa (I. Marynova, T. Filipova); German Center for Infection Research, Hamburg-Lübeck-Borstel-Riems, Germany (S. Niemann)

Main Article

Figure 4

Maximum parsimony phylogenies of 3 Mycobacterium tuberculosis complex Beijing clades in Ukraine: Europe/Russia W148 outbreak (A), Ukraine outbreak (B), and Central Asian outbreak (C). Mutations mediating drug resistance to different antibiotics are color coded. Same color indicates identical mutation. Numbers on branches indicate the number of unique mutations. EMB, ethambutol; ETH, ethionamide; Fq, fluoroquinolones; INH, isoniazid; Inj, second-line injectable drugs (amikacin, kanamycin, capreom

Figure 4. Maximum parsimony phylogenies of 3 Mycobacterium tuberculosis complex Beijing clades in Ukraine: Europe/Russia W148 outbreak (A), Ukraine outbreak (B), and Central Asian outbreak (C). Mutations mediating drug resistance to different antibiotics are color coded. Same color indicates identical mutation. Numbers on branches indicate the number of unique mutations. EMB, ethambutol; ETH, ethionamide; Fq, fluoroquinolones; INH, isoniazid; Inj, second-line injectable drugs (amikacin, kanamycin, capreomycin); KAN, kanamycin; PAS, para-aminosalicylic acid; PTH, prothionamide; PZA, pyrazinamide; RIF, rifampin; STR, streptomycin.

Main Article

Page created: February 20, 2020
Page updated: February 20, 2020
Page reviewed: February 20, 2020
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